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Descriptor English: Leukotrienes
Descriptor Spanish: Leucotrienos
Descriptor leucotrienos
Entry term(s) leucotrieno
Scope note: Familia de compuestos biológicamente activos derivados del ácido araquidónico por metabolismo oxidativo por la vía de la 5-lipooxigenasa. Participan en las reacciones de defensa del hospedador y en afecciones fisiopatológicas tales como la hipersensibilidad inmediata y la inflamación. Tienen potentes acciones sobre muchos órganos y sistemas esenciales, incluidos los sistemas cardiovascular, pulmonar y nervioso central así como en el tracto gastrointestinal y el sistema inmunitario.
Descriptor Portuguese: Leucotrienos
Descriptor French: Leucotriènes
Tree number(s): D10.251.355.255.100.450
D10.251.355.310.166.887
D23.469.050.175.450
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015289
Scope note: A family of biologically active compounds derived from arachidonic acid by oxidative metabolism through the 5-lipoxygenase pathway. They participate in host defense reactions and pathophysiological conditions such as immediate hypersensitivity and inflammation. They have potent actions on many essential organs and systems, including the cardiovascular, pulmonary, and central nervous system as well as the gastrointestinal tract and the immune system.
Annotation: general or unspecified; prefer specifics
Allowable Qualifiers: AD administration et posologie
AE effets indésirables
AG agonistes
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
DF déficit
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PH physiologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Entry Combination: antagonists & inhibitors:Leukotriene Antagonists
Related: Récepteurs aux leucotriènes MeSH
DeCS ID: 28158
Unique ID: D015289
NLM Classification: QU 90
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1989/01/01
Date of Entry: 1988/05/24
Revision Date: 2020/05/27
Leucotriènes - Preferred
Concept UI M0023536
Preferred term Leucotriènes



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