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Descriptor English: Leukotrienes
Descriptor Spanish: Leucotrienos
Descriptor leucotrienos
Entry term(s) leucotrieno
Scope note: Familia de compuestos biológicamente activos derivados del ácido araquidónico por metabolismo oxidativo por la vía de la 5-lipooxigenasa. Participan en las reacciones de defensa del hospedador y en afecciones fisiopatológicas tales como la hipersensibilidad inmediata y la inflamación. Tienen potentes acciones sobre muchos órganos y sistemas esenciales, incluidos los sistemas cardiovascular, pulmonar y nervioso central así como en el tracto gastrointestinal y el sistema inmunitario.
Descriptor Portuguese: Leucotrienos
Descriptor French: Leucotriènes
Entry term(s): Leukotriene
Tree number(s): D10.251.355.255.100.450
D10.251.355.310.166.887
D23.469.050.175.450
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015289
Scope note: A family of biologically active compounds derived from arachidonic acid by oxidative metabolism through the 5-lipoxygenase pathway. They participate in host defense reactions and pathophysiological conditions such as immediate hypersensitivity and inflammation. They have potent actions on many essential organs and systems, including the cardiovascular, pulmonary, and central nervous system as well as the gastrointestinal tract and the immune system.
Annotation: general or unspecified; prefer specifics
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Entry Combination: antagonists & inhibitors:Leukotriene Antagonists
Previous Indexing: Arachidonic Acids (1979-1988)
Leukotrienes B (1983-1988)
SRS-A (1979-1988)
Public MeSH Note: 89
History Note: 89
Related: Receptors, Leukotriene MeSH
DeCS ID: 28158
Unique ID: D015289
NLM Classification: QU 90
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1989/01/01
Date of Entry: 1988/05/24
Revision Date: 2020/05/27
Leukotrienes - Preferred
Concept UI M0023536
Scope note A family of biologically active compounds derived from arachidonic acid by oxidative metabolism through the 5-lipoxygenase pathway. They participate in host defense reactions and pathophysiological conditions such as immediate hypersensitivity and inflammation. They have potent actions on many essential organs and systems, including the cardiovascular, pulmonary, and central nervous system as well as the gastrointestinal tract and the immune system.
Preferred term Leukotrienes
Entry term(s) Leukotriene



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