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Descriptor English: Guanosine 5'-O-(3-Thiotriphosphate)
Descriptor Spanish: Guanosina 5'-O-(3-Tiotrifosfato)
Descriptor Portuguese: Guanosina 5'-O-(3-Tiotrifosfato)
Descriptor French: Guanosine 5'-O-(3-thiotriphosphate)
Entry term(s): GTP gamma S
GTPgammaS
Guanosine 5'-(3-O-Thio)Triphosphate
Guanosine 5'-(gamma-S)Triphosphate
gamma S, GTP
gamma Thio GTP
gamma-Thio-GTP
Tree number(s): D02.886.765.380
D13.695.667.454.504.380
D13.695.827.426.504.380
D13.695.900.380
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D016244
Scope note: Guanosine 5'-(trihydrogen diphosphate), monoanhydride with phosphorothioic acid. A stable GTP analog which enjoys a variety of physiological actions such as stimulation of guanine nucleotide-binding proteins, phosphoinositide hydrolysis, cyclic AMP accumulation, and activation of specific proto-oncogenes.
Annotation: /biosyn /physiol permitted
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Registry Number: 37589-80-3
CAS Type 1 Name: Guanosine 5'-(trihydrogen diphosphate), P'-anhydride with phosphorothioic acid
Previous Indexing: Guanosine Triphosphate (1972-1990)
Thionucleotides (1977-1990)
Public MeSH Note: 91
History Note: 91
Entry Version: GUANOSINE 5 O 3 THIOTRIPHOSPHATE
DeCS ID: 28973
Unique ID: D016244
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1990/05/07
Revision Date: 2005/06/30
Guanosine 5'-O-(3-Thiotriphosphate) - Preferred
Concept UI M0024807
Scope note Guanosine 5'-(trihydrogen diphosphate), monoanhydride with phosphorothioic acid. A stable GTP analog which enjoys a variety of physiological actions such as stimulation of guanine nucleotide-binding proteins, phosphoinositide hydrolysis, cyclic AMP accumulation, and activation of specific proto-oncogenes.
Preferred term Guanosine 5'-O-(3-Thiotriphosphate)
Entry term(s) GTP gamma S
GTPgammaS
Guanosine 5'-(3-O-Thio)Triphosphate
Guanosine 5'-(gamma-S)Triphosphate
gamma S, GTP
gamma Thio GTP
gamma-Thio-GTP



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