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Descriptor English: | Calcimycin | ||||||
Descriptor Spanish: |
Calcimicina
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Descriptor Portuguese: | Calcimicina | ||||||
Descriptor French: | A-23187 | ||||||
Tree number(s): |
D02.355.291.933.125 D02.540.576.625.125 D03.633.100.221.173 D04.345.241.654.125 D04.345.674.625.125 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000001 | ||||||
Scope note: | An ionophorous, polyether antibiotic from Streptomyces chartreusensis. It binds and transports CALCIUM and other divalent cations across membranes and uncouples oxidative phosphorylation while inhibiting ATPase of rat liver mitochondria. The substance is used mostly as a biochemical tool to study the role of divalent cations in various biological systems. |
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Allowable Qualifiers: |
AA analogues et dérivés AD administration et posologie AE effets indésirables AG agonistes AI antagonistes et inhibiteurs AN analyse BI biosynthèse BL sang CF liquide cérébrospinal CH composition chimique CL classification CS synthèse chimique EC économie HI histoire IM immunologie IP isolement et purification ME métabolisme PD pharmacologie PK pharmacocinétique PO intoxication RE effets des radiations SD ressources et distribution ST normes TO toxicité TU usage thérapeutique UR urine |
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Pharm Action: |
Anti-Bacterial Agents Calcium Ionophores |
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Registry Number: | 37H9VM9WZL | ||||||
CAS Type 1 Name: | 4-Benzoxazolecarboxylic acid, 5-(methylamino)-2-((3,9,11-trimethyl-8-(1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl)-1,7-dioxaspiro(5.5)undec-2-yl)methyl)-, (6S-(6alpha(2S*,3S*),8beta(R*),9beta,11alpha))- | ||||||
DeCS ID: | 29212 | ||||||
Unique ID: | D000001 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 1984/01/01 | ||||||
Date of Entry: | 1974/11/19 | ||||||
Revision Date: | 2016/05/27 |
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PRODUITS CHIMIQUES ET PHARMACEUTIQUES
Composés chimiques organiques [D02]Composés chimiques organiques -
PRODUITS CHIMIQUES ET PHARMACEUTIQUES
Composés chimiques organiques [D02]Composés chimiques organiques -
PRODUITS CHIMIQUES ET PHARMACEUTIQUES
Composés hétérocycliques [D03]Composés hétérocycliques -
PRODUITS CHIMIQUES ET PHARMACEUTIQUES
Composés polycycliques [D04]Composés polycycliques -
PRODUITS CHIMIQUES ET PHARMACEUTIQUES
Composés polycycliques [D04]Composés polycycliques
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