DeCS

Descriptor English:

Clomipramine

Descriptor Spanish:

Clomipramina

Spanish from Spain

Descriptor	clomipramina
Entry term(s)	clorimipramina
Scope note:	Antidepresivo tricíclico similar a la IMIPRAMINA, que inhibe selectivamente la captación de serotonina en el encéfalo. Se absorbe fácilmente en el tracto gastrointestinal y, en el hígado, sufre una desmetilación para formar su principal metabolito activo, la desmetilclomipramina.

Descriptor Portuguese:

Clomipramina

Descriptor French:

Clomipramine

Tree number(s):

D03.633.300.240.194

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D002997

Scope note:

A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Pharm Action:

Antidepressive Agents, Tricyclic
Serotonin Uptake Inhibitors

Registry Number:

NUV44L116D

CAS Type 1 Name:

5H-Dibenz(b,f)azepine-5-propanamine, 3-chloro-10,11-dihydro-N,N-dimethyl-

DeCS ID:

3022

Unique ID:

D002997

NLM Classification:

QV 77.5