| Descriptor English: | Apolipoprotein A-II | ||||||
| Descriptor Spanish: |
Apolipoproteína A-II
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| Descriptor Portuguese: | Apolipoproteína A-II | ||||||
| Descriptor French: | Apolipoprotéine A-II | ||||||
| Entry term(s): |
Apo A II Isoproteins Apo A-2 Apo A-II Apo A-II Isoproteins Apo A2 Apo AII ApoA-2 ApoA-II Apolipoprotein A 2 Apolipoprotein A II Apolipoprotein A II Isoproteins Apolipoprotein A-2 Apolipoprotein A-II Isoproteins Apolipoprotein A2 Apolipoprotein AII Pro Apo A II Pro Apolipoprotein A II Pro-Apo A-II Pro-Apolipoprotein A-II Proapolipoprotein A II Proapolipoprotein A-II |
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| Tree number(s): |
D10.532.091.200.150 D12.776.070.400.200.150 D12.776.521.120.200.150 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D016633 | ||||||
| Scope note: | The second most abundant protein component of HIGH DENSITY LIPOPROTEINS or HDL. It has a high lipid affinity and is known to displace APOLIPOPROTEIN A-I from HDL particles and generates a stable HDL complex. ApoA-II can modulate the activation of LECITHIN CHOLESTEROL ACYLTRANSFERASE in the presence of APOLIPOPROTEIN A-I, thus affecting HDL metabolism. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Apolipoproteins (1977-1984) Apolipoproteins A (1985-1991) |
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| Public MeSH Note: | 1992; APOLIPOPROTEIN A-II was indexed under APOLIPOPROTEINS A 1985-1991, under APOLIPOPROTEINS 1978-1984; PRO-APOLIPOPROTEIN A-II was indexed under APOLIPOPROTEINS A & PROTEIN PRECURSORS 1985-2006; APOLIPOPROTEIN A-II ISOPROTEINS was indexed under APOLIPOPROTEINS A 1983-2006 |
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| Online Note: | use APOLIPOPROTEIN A-II (NM) to search APOLIPOPROTEIN A-II 1980-91 |
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| History Note: | 1992 (1978); for PRO-APOLIPOPROTEIN A-II (NM) use APOLIPOPROTEINS A & PROTEIN PRECURSORS 1985-2006; for APOLIPOPROTEIN A-II ISOPROTEINS (NM) use APOLIPOPROTEINS A 1983-2006 |
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| DeCS ID: | 30251 | ||||||
| Unique ID: | D016633 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1992/01/01 | ||||||
| Date of Entry: | 1991/01/24 | ||||||
| Revision Date: | 2006/07/05 |
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CHEMICALS AND DRUGS
Lipids [D10]Lipids -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Apolipoprotein A-II
- Preferred
Apolipoprotein A-II Isoproteins
- Narrower
Pro-Apolipoprotein A-II
- Narrower
| Concept UI |
M0025349 |
| Scope note | The second most abundant protein component of HIGH DENSITY LIPOPROTEINS or HDL. It has a high lipid affinity and is known to displace APOLIPOPROTEIN A-I from HDL particles and generates a stable HDL complex. ApoA-II can modulate the activation of LECITHIN CHOLESTEROL ACYLTRANSFERASE in the presence of APOLIPOPROTEIN A-I, thus affecting HDL metabolism. |
| Preferred term | Apolipoprotein A-II |
| Entry term(s) |
Apo A-2 Apo A-II Apo A2 Apo AII ApoA-2 ApoA-II Apolipoprotein A 2 Apolipoprotein A II Apolipoprotein A-2 Apolipoprotein A2 Apolipoprotein AII |
| Concept UI |
M0492280 |
| Preferred term | Apolipoprotein A-II Isoproteins |
| Entry term(s) |
Apo A II Isoproteins Apo A-II Isoproteins Apolipoprotein A II Isoproteins |
| Concept UI |
M0140943 |
| Preferred term | Pro-Apolipoprotein A-II |
| Entry term(s) |
Pro Apo A II Pro Apolipoprotein A II Pro-Apo A-II Proapolipoprotein A II Proapolipoprotein A-II |
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