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Descriptor English: Antigenic Modulation
Descriptor Spanish: Modulación Antigénica
Descriptor modulación antigénica
Scope note: Pérdida de antígeno detectable de la superficie de una célula después de una incubación con anticuerpos. Es un método en el que algunos tumores no son detectados por el sistema inmunitario. La modulación antigénica de los antígenos diana reduce también la efectividad terapéutica del tratamiento por anticuerpos monoclonales.
Descriptor Portuguese: Modulação Antigênica
Descriptor French: Modulation antigénique
Entry term(s): Antigenic Modulations
Modulation, Antigenic
Modulations, Antigenic
Tree number(s): G12.122.140
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D016525
Scope note: Loss of detectable antigen from the surface of a cell after incubation with antibodies. This is one method in which some tumors escape detection by the immune system. Antigenic modulation of target antigens also reduces the therapeutic effectiveness of treatment by monoclonal antibodies.
Allowable Qualifiers: DE drug effects
ES ethics
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Antigen-Antibody Reactions (1968-1989)
Antigens, Surface/analysis (1979-1991)
Antigens, Surface/immunology (1979-1988)
Public MeSH Note: 92
History Note: 92
DeCS ID: 30261
Unique ID: D016525
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1992/01/01
Date of Entry: 1991/06/21
Revision Date: 2016/06/02
Antigenic Modulation - Preferred
Concept UI M0025224
Scope note Loss of detectable antigen from the surface of a cell after incubation with antibodies. This is one method in which some tumors escape detection by the immune system. Antigenic modulation of target antigens also reduces the therapeutic effectiveness of treatment by monoclonal antibodies.
Preferred term Antigenic Modulation
Entry term(s) Antigenic Modulations
Modulation, Antigenic
Modulations, Antigenic



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