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Descriptor English: Antibody Affinity
Descriptor Spanish: Afinidad de Anticuerpos
Descriptor Portuguese: Afinidade de Anticorpos
Descriptor French: Affinité des anticorps
Entry term(s): Affinities, Antibody
Affinity, Antibody
Antibody Affinities
Antibody Avidities
Antibody Avidity
Avidities, Antibody
Avidity, Antibody
Tree number(s): G12.040
G12.122.125
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000915
Scope note: A measure of the binding strength between antibody and a simple hapten or antigen determinant. It depends on the closeness of stereochemical fit between antibody combining sites and antigen determinants, on the size of the area of contact between them, and on the distribution of charged and hydrophobic groups. It includes the concept of "avidity," which refers to the strength of the antigen-antibody bond after formation of reversible complexes.
Annotation: do not confuse with BINDING SITES, ANTIBODY or ANTIGENIC DETERMINANTS
Allowable Qualifiers: DE drug effects
ES ethics
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Antibodies (1966-1978)
Antigen-Antibody Reactions (1966-1978)
Antigenic Determinants (1970-1978)
Binding Sites, Antibody (1973-1978)
Public MeSH Note: 79
History Note: 79
DeCS ID: 923
Unique ID: D000915
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1979/01/01
Date of Entry: 1977/12/02
Revision Date: 2016/06/02
Antibody Affinity - Preferred
Concept UI M0001362
Scope note A measure of the binding strength between antibody and a simple hapten or antigen determinant. It depends on the closeness of stereochemical fit between antibody combining sites and antigen determinants, on the size of the area of contact between them, and on the distribution of charged and hydrophobic groups. It includes the concept of "avidity," which refers to the strength of the antigen-antibody bond after formation of reversible complexes.
Preferred term Antibody Affinity
Entry term(s) Affinities, Antibody
Affinity, Antibody
Antibody Affinities
Antibody Avidity - Narrower
Concept UI M0001363
Preferred term Antibody Avidity
Entry term(s) Antibody Avidities
Avidities, Antibody
Avidity, Antibody



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