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Descriptor English: Receptors, Phencyclidine
Descriptor Spanish: Receptores de Fenciclidina
Descriptor receptores de fenciclidina
Entry term(s) receptores de PCP
Scope note: Estructuras moleculares o sitios específicos que se encuentran en las membranas celulares o en células con las que reacciona la fenciclidina (PCP) o a los que esta se une para provocar la respuesta específica de la célula al compuesto. Diversos estudios han demostrado la presencia de múltiples sitios receptores de la PCP: el sitio receptor de PCP sigma, que se une tanto a la PCP como a opiáceos psicoticomiméticos, pero no a ciertos antipsicóticos, y el sitio PCP, que se une selectivamente a análogos de la PCP.
Descriptor Portuguese: Receptores da Fenciclidina
Descriptor French: Récepteurs de la phencyclidine
Entry term(s): PCP Receptor
PCP Receptors
Phencyclidine Receptors
Phencylidine Receptor
Receptor, PCP
Receptor, Phencylidine
Receptors, PCP
Tree number(s): D12.776.827.550
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D017478
Scope note: Specific sites or molecular structures on cell membranes or in cells with which phencyclidine reacts or to which it binds to elicit the specific response of the cell to phencyclidine. Studies have demonstrated the presence of multiple receptor sites for PCP. These are the PCP/sigma site, which binds both PCP and psychotomimetic opiates but not certain antipsychotics, and the PCP site, which selectively binds PCP analogs.
Allowable Qualifiers: AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Previous Indexing: Receptors, Drug (1981-1983)
Receptors, Synaptic (1983-1992)
Public MeSH Note: 93; PHENCYCLIDINE RECEPTOR was indexed under RECEPTORS, SYNAPTIC 1983-92 & RECEPTORS, DRUG 1981-83
Online Note: use RECEPTORS, PHENCYCLIDINE (NM) to search PHENCYCLIDINE RECEPTOR 1981-92
History Note: 93; was PHENCYCLIDINE RECEPTOR (NM) 1981-92
Entry Version: RECEPT PHENCYCLIDINE
DeCS ID: 30548
Unique ID: D017478
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1993/01/01
Date of Entry: 1992/05/22
Revision Date: 1997/06/20
Receptors, Phencyclidine - Preferred
Concept UI M0026514
Scope note Specific sites or molecular structures on cell membranes or in cells with which phencyclidine reacts or to which it binds to elicit the specific response of the cell to phencyclidine. Studies have demonstrated the presence of multiple receptor sites for PCP. These are the PCP/sigma site, which binds both PCP and psychotomimetic opiates but not certain antipsychotics, and the PCP site, which selectively binds PCP analogs.
Preferred term Receptors, Phencyclidine
Entry term(s) PCP Receptor
PCP Receptors
Phencyclidine Receptors
Phencylidine Receptor
Receptor, PCP
Receptor, Phencylidine
Receptors, PCP



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