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Descriptor English: Clonal Deletion
Descriptor Spanish: Supresión Clonal
Descriptor deleción clonal
Entry term(s) aborto clonal
supresión clonal
Scope note: Eliminación, por MUERTE CELULAR, de linfocitos inmaduros que interactúan con antígenos durante la maduración. En lo que respecta a los linfocitos T, esto ocurre en el timo y garantiza que los linfocitos T maduros sean autotolerantes. Los linfocitos B también pueden sufrir supresión clonal.
Descriptor Portuguese: Deleção Clonal
Descriptor French: Délétion clonale
Entry term(s): Abortion, Clonal
Abortions, Clonal
Clonal Abortion
Clonal Abortions
Clonal Deletions
Deletion, Clonal
Deletions, Clonal
Tree number(s): G12.535.425.120
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D017637
Scope note: Removal, via CELL DEATH, of immature lymphocytes that interact with antigens during maturation. For T-lymphocytes this occurs in the thymus and ensures that mature T-lymphocytes are self tolerant. B-lymphocytes may also undergo clonal deletion.
Annotation: a form of immune tolerance
Allowable Qualifiers: DE drug effects
ES ethics
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Clone Cells (1978-1993)
Immune Tolerance (1978-1993)
specific cell/immunology (1978-1993)
Public MeSH Note: 94
History Note: 94
Related: Apoptosis MeSH
DeCS ID: 31557
Unique ID: D017637
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1994/01/01
Date of Entry: 1993/02/16
Revision Date: 2016/06/16
Clonal Deletion - Preferred
Concept UI M0026706
Scope note Removal, via CELL DEATH, of immature lymphocytes that interact with antigens during maturation. For T-lymphocytes this occurs in the thymus and ensures that mature T-lymphocytes are self tolerant. B-lymphocytes may also undergo clonal deletion.
Preferred term Clonal Deletion
Entry term(s) Clonal Deletions
Deletion, Clonal
Deletions, Clonal
Clonal Abortion - Related but not broader or narrower
Concept UI M0026705
Preferred term Clonal Abortion
Entry term(s) Abortion, Clonal
Abortions, Clonal
Clonal Abortions



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