Descriptor English: | Self Tolerance | ||||||
Descriptor Spanish: |
Autotolerancia
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Descriptor Portuguese: | Tolerância a Antígenos Próprios | ||||||
Descriptor French: | Autotolérance | ||||||
Entry term(s): |
Self Tolerances Tolerance, Self Tolerances, Self |
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Tree number(s): |
G12.535.425.800 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D017634 | ||||||
Scope note: | The normal lack of the ability to produce an immunological response to autologous (self) antigens. A breakdown of self tolerance leads to autoimmune diseases. The ability to recognize the difference between self and non-self is the prime function of the immune system. |
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Annotation: | a form of immune tolerance |
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Allowable Qualifiers: |
DE drug effects ES ethics GE genetics IM immunology PH physiology RE radiation effects |
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Previous Indexing: |
Immune Tolerance (1973-1993) |
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Public MeSH Note: | 94 |
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History Note: | 94 |
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Related: |
Autoimmune Diseases
MeSH Clonal Anergy MeSH Clonal Deletion MeSH | ||||||
DeCS ID: | 31052 | ||||||
Unique ID: | D017634 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 1994/01/01 | ||||||
Date of Entry: | 1993/02/16 | ||||||
Revision Date: | 2016/06/23 |
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PHENOMENA AND PROCESSES
Immune System Phenomena [G12]Immune System Phenomena
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Self Tolerance
- Preferred
Concept UI |
M0026701 |
Scope note | The normal lack of the ability to produce an immunological response to autologous (self) antigens. A breakdown of self tolerance leads to autoimmune diseases. The ability to recognize the difference between self and non-self is the prime function of the immune system. |
Preferred term | Self Tolerance |
Entry term(s) |
Self Tolerances Tolerance, Self Tolerances, Self |
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