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Descriptor English: Superoxides
Descriptor Spanish: Superóxidos
Descriptor superóxidos
Entry term(s) radical superóxido
Scope note: Compuestos altamente reactivos producidos cuando el oxígeno es reducido en un único electrón. En los sistemas biológicos pueden ser generados durante la función catalítica normal de una serie de enzimas y durante la oxidación de la hemoglobina a METAHEMOGLOBINA. En los organismos vivos, la SUPEROXIDO DISMUTASA protege a la célula de los efectos lesivos del superóxido.
Descriptor Portuguese: Superóxidos
Descriptor French: Superoxydes
Entry term(s): Superoxide
Superoxide Anion
Superoxide Radical
Tree number(s): D01.248.497.158.685.750.850
D01.339.431.374.850
D01.650.550.750.800
D02.389.338.732
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013481
Scope note: Highly reactive compounds produced when oxygen is reduced by a single electron. In biological systems, they may be generated during the normal catalytic function of a number of enzymes and during the oxidation of hemoglobin to METHEMOGLOBIN. In living organisms, SUPEROXIDE DISMUTASE protects the cell from the deleterious effects of superoxides.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Oxidants
Registry Number: 11062-77-4
CAS Type 1 Name: Superoxide
Previous Indexing: Anions (1974)
Oxygen (1974)
Public MeSH Note: 1994; was SUPEROXIDE 1975-1993 (see under OXYGEN 1975-1983)
Online Note: use SUPEROXIDES to search SUPEROXIDE 1975-1993
History Note: 1994; was SUPEROXIDE 1975-1993 (see under OXYGEN 1975-1983)
Related: Reactive Oxygen Species MeSH
Respiratory Burst MeSH
Superoxide Dismutase MeSH
DeCS ID: 31785
Unique ID: D013481
NLM Classification: QV 312
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1984/01/01
Date of Entry: 1974/11/11
Revision Date: 2015/06/23
Superoxides - Preferred
Concept UI M0020825
Scope note Highly reactive compounds produced when oxygen is reduced by a single electron. In biological systems, they may be generated during the normal catalytic function of a number of enzymes and during the oxidation of hemoglobin to METHEMOGLOBIN. In living organisms, SUPEROXIDE DISMUTASE protects the cell from the deleterious effects of superoxides.
Preferred term Superoxides
Entry term(s) Superoxide
Superoxide Anion
Superoxide Radical



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