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Descriptor English: Receptor, ErbB-2
Descriptor Spanish: Receptor ErbB-2
Descriptor receptor ErbB-2
Entry term(s) antígeno CD340
antígenos CD340
p185(c-neu)
proteína HER 2 de protooncogén
proteína HER-2 de protooncogén
proteína c erbB 2
proteína c-erbB-2
proteína c-erbB-2 de protooncogén
proteína de protooncogén HER 2
proteína de protooncogén HER-2
proteína de protooncogén neu
proteína p185(neu) de protooncogén
proteína p185erbB2
proteína protooncogénica Neu
proteína protooncogénica erbB 2
proteína tirosina cinasa del receptor erbB-2
proteínas protooncogénicas c erbB 2
proteínas protooncogénicas c-erbB-2
receptor neu
Scope note: Receptor de la superficie celular con actividad tirosina cinasa que se sobreexpresa en un número significativo de ADENOCARCINOMAS. Tiene una amplia homología y puede heterodimerizarse con el RECEPTOR DEL FACTOR DE CRECIMIENTO EPIDÉRMICO, el RECEPTOR ERBB-3, y el RECEPTOR ERB-4. La activación del receptor erbB-2 tiene lugar por la formación del heterodímero con un miembro de la familia del receptor erbB unido al ligando.
Descriptor Portuguese: Receptor ErbB-2
Descriptor French: Récepteur ErbB-2
Entry term(s): Antigens, CD340
CD340 Antigen
CD340 Antigens
Erb b2 Receptor Tyrosine Kinases
Erb-b2 Receptor Tyrosine Kinases
ErbB-2 Receptor
HER 2 Proto Oncogene Protein
HER-2 Proto-Oncogene Protein
Metastatic Lymph Node Gene 19 Protein
Neu Receptor
Neu, Proto-oncogene Protein
Oncogene Protein HER 2
Oncogene Protein HER-2
Proto Oncogene Protein HER 2
Proto Oncogene Proteins c erbB 2
Proto-Oncogene Protein HER-2
Proto-Oncogene Protein p185(neu)
Proto-Oncogene Protein, HER-2
Proto-Oncogene Protein, erbB-2
Proto-Oncogene Protein, neu
Proto-Oncogene Proteins c-erbB-2
Proto-oncogene Protein Neu
Receptor, Neu
Receptors, erbB-2
Tyrosine Kinase type Cell Surface Receptor HER2
Tyrosine Kinase-type Cell Surface Receptor HER2
c erbB 2 Protein
c-ErbB-2, Proto-oncogene
c-erbB-2 Protein
erbB 2 Proto Oncogene Protein
erbB 2 Receptor Protein Tyrosine Kinase
erbB-2 Proto-Oncogene Protein
erbB-2 Receptor Protein-Tyrosine Kinase
erbB-2 Receptors
neu Proto Oncogene Protein
neu Proto-Oncogene Protein
p185(c-neu)
p185erbB2 Protein
Tree number(s): D08.811.913.696.620.682.725.400.009.400
D12.776.476.568.400.009.400
D12.776.543.750.630.009.400
D12.776.543.750.750.400.074.400
D12.776.624.664.700.642
D23.050.301.500.600.700
D23.050.705.552.600.550
D23.101.140.642
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D018719
Scope note: A cell surface protein-tyrosine kinase receptor that is overexpressed in a variety of ADENOCARCINOMAS. It has extensive homology to and heterodimerizes with the EGF RECEPTOR, the ERBB-3 RECEPTOR, and the ERBB-4 RECEPTOR. Activation of the erbB-2 receptor occurs through heterodimer formation with a ligand-bound erbB receptor family member.
Allowable Qualifiers: AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Registry Number: EC 2.7.10.1
Previous Indexing: Epidermal Growth Factor Receptor Protein-Tyrosine Kinase (1994)
Phosphoproteins (1985)
Proto-Oncogene Proteins (1986-1994)
Public MeSH Note: 2019; for ERB-B2 RECEPTOR TYROSINE KINASES see ERBB RECEPTORS 2017-2019; see PROTO-ONCOGENE PROTEINS C-ERBB-2 1995-1999; for PROTO-ONCOGENE PROTEIN ERBB-2 see EPIDERMAL GROWTH FACTOR RECEPTOR PROTEIN-TYROSINE KINASE 1994, PROTO-ONCOGENE PROTEINS 1986-1994, and PHOSPHOPROTEINS 1985;
History Note: 2019 (1995)
Related: Genes, erbB-2 MeSH
Trastuzumab MeSH
DeCS ID: 32062
Unique ID: D018719
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1995/01/01
Date of Entry: 1999/11/04
Revision Date: 2018/03/01
Receptor, ErbB-2 - Preferred
Concept UI M0028048
Scope note A cell surface protein-tyrosine kinase receptor that is overexpressed in a variety of ADENOCARCINOMAS. It has extensive homology to and heterodimerizes with the EGF RECEPTOR, the ERBB-3 RECEPTOR, and the ERBB-4 RECEPTOR. Activation of the erbB-2 receptor occurs through heterodimer formation with a ligand-bound erbB receptor family member.
Preferred term Receptor, ErbB-2
Entry term(s) Antigens, CD340
CD340 Antigen
CD340 Antigens
Erb b2 Receptor Tyrosine Kinases
Erb-b2 Receptor Tyrosine Kinases
ErbB-2 Receptor
HER 2 Proto Oncogene Protein
HER-2 Proto-Oncogene Protein
Metastatic Lymph Node Gene 19 Protein
Neu Receptor
Neu, Proto-oncogene Protein
Oncogene Protein HER 2
Oncogene Protein HER-2
Proto Oncogene Protein HER 2
Proto Oncogene Proteins c erbB 2
Proto-Oncogene Protein HER-2
Proto-Oncogene Protein p185(neu)
Proto-Oncogene Protein, HER-2
Proto-Oncogene Protein, erbB-2
Proto-Oncogene Protein, neu
Proto-Oncogene Proteins c-erbB-2
Proto-oncogene Protein Neu
Receptor, Neu
Receptors, erbB-2
Tyrosine Kinase type Cell Surface Receptor HER2
Tyrosine Kinase-type Cell Surface Receptor HER2
c erbB 2 Protein
c-ErbB-2, Proto-oncogene
c-erbB-2 Protein
erbB 2 Proto Oncogene Protein
erbB 2 Receptor Protein Tyrosine Kinase
erbB-2 Proto-Oncogene Protein
erbB-2 Receptor Protein-Tyrosine Kinase
erbB-2 Receptors
neu Proto Oncogene Protein
neu Proto-Oncogene Protein
p185(c-neu)
p185erbB2 Protein



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