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Descriptor English: Chemokine CCL5
Descriptor Spanish: Quimiocina CCL5
Descriptor quimiocina CCL5
Entry term(s) RANTES
quimiocinas CCL5
Scope note: Quimiocina de tipo CC que atrae a EOSINÓFILOS, MONOCITOS y LINFOCITOS. Es una potente y selectiva quimiotaxina de eosinófilos que es almacenada en y liberada en las PLAQUETAS y LINFOCITOS T activados. La quimiocina CCL5 es específica para los RECEPTORES CCR1, los RECEPTORES CCR3 y los RECEPTORES CCR5. El acrónimo inglés RANTES hace referencia al quimiotáctico expresado y segregado por las células T normales y regulado por activación.
Descriptor Portuguese: Quimiocina CCL5
Descriptor French: Chimiokine CCL5
Entry term(s): CCL5 Chemokine
CCL5, Chemokine
Chemokine, CCL5
RANTES
RANTES Protein, T Cell
RANTES Protein, T-Cell
T-Cell RANTES Protein
Tree number(s): D12.644.276.374.200.110.250
D12.776.467.374.200.110.250
D23.125.300.110.250
D23.469.200.110.250
D23.529.374.200.110.250
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D018946
Scope note: A CC-type chemokine that is a chemoattractant for EOSINOPHILS; MONOCYTES; and LYMPHOCYTES. It is a potent and selective eosinophil chemotaxin that is stored in and released from PLATELETS and activated T-LYMPHOCYTES. Chemokine CCL5 is specific for CCR1 RECEPTORS; CCR3 RECEPTORS; and CCR5 RECEPTORS. The acronym RANTES refers to Regulated on Activation, Normal T Expressed and Secreted.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Lymphokines (1988-1995)
Public MeSH Note: 2008; see RANTES 1996-2007; RANTES PROTEIN, T-CELL was indexed under LYMPHOKINES 1988-95; RANTES PROTEIN, MURINE was indexed under LYMPHOKINES 1992-95
History Note: 2008(1996)
DeCS ID: 32633
Unique ID: D018946
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1996/01/01
Date of Entry: 1995/02/21
Revision Date: 2007/07/09
Chemokine CCL5 - Preferred
Concept UI M0028315
Scope note A CC-type chemokine that is a chemoattractant for EOSINOPHILS; MONOCYTES; and LYMPHOCYTES. It is a potent and selective eosinophil chemotaxin that is stored in and released from PLATELETS and activated T-LYMPHOCYTES. Chemokine CCL5 is specific for CCR1 RECEPTORS; CCR3 RECEPTORS; and CCR5 RECEPTORS. The acronym RANTES refers to Regulated on Activation, Normal T Expressed and Secreted.
Preferred term Chemokine CCL5
Entry term(s) CCL5 Chemokine
CCL5, Chemokine
Chemokine, CCL5
RANTES
RANTES Protein, T Cell
RANTES Protein, T-Cell
T-Cell RANTES Protein



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