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Descriptor English: Chemokine CCL18
Descriptor Spanish: Quimiocina CCL18
Descriptor quimiocina CCL18
Entry term(s) proteína AMAC-1
proteína MIP-4
proteína inflamatoria de los macrófagos 4
quimiocina pulmonar y regulada por activación
Scope note: Quimiocina de tipo C-C que se expresa ampliamente en el pulmón, ganglios linfáticos, placenta y médula ósea; también es expresada por las CÉLULAS DENDRÍTICAS del CENTRO GERMINAL y por los MACRÓFAGOS de la sangre. Actúa como factor quimiotáctico que atrae específicamente a los LINFOCITOS, especialmente de tipo B, hacia los folículos linfáticos y a las células T vírgenes hacia las células dendríticas y linfocitos T activados. No atrae a los MONOCITOS ni a los GRANULOCITOS.
Descriptor Portuguese: Quimiocina CCL18
Descriptor French: Chimiokine CCL18
Entry term(s): AMAC 1 Protein
AMAC-1 Protein
CCL18, Chemokine
MIP 4 Protein
MIP-4 Protein
Macrophage Inflammatory Protein 4
Pulmonary and Activation Regulated Chemokine
Pulmonary and Activation-Regulated Chemokine
Tree number(s): D12.644.276.374.200.110.100
D12.644.276.374.200.600.075
D12.776.467.374.200.110.100
D12.776.467.374.200.600.075
D23.125.300.110.100
D23.125.300.600.250
D23.469.200.110.100
D23.469.200.600.075
D23.529.374.200.110.100
D23.529.374.200.600.075
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000075366
Scope note: A CC-type chemokine highly expressed in the lungs, lymph nodes, placenta, and bone marrow; it is also expressed by DENDRITIC CELLS in the GERMINAL CENTER, and peripheral blood MACROPHAGES. It functions as a chemotactic factor that specifically attracts LYMPHOCYTES, especially B-Cells, into lymph node follicles, and naive T-cells towards dendritic cells and activated T-cells. It does not attract MONOCYTES or GRANULOCYTES.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Chemokines, CC (1998-2017)
Public MeSH Note: 2018
History Note: 2018
DeCS ID: 57050
Unique ID: D000075366
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/06/01
Chemokine CCL18 - Preferred
Concept UI M000630242
Scope note A CC-type chemokine highly expressed in the lungs, lymph nodes, placenta, and bone marrow; it is also expressed by DENDRITIC CELLS in the GERMINAL CENTER, and peripheral blood MACROPHAGES. It functions as a chemotactic factor that specifically attracts LYMPHOCYTES, especially B-Cells, into lymph node follicles, and naive T-cells towards dendritic cells and activated T-cells. It does not attract MONOCYTES or GRANULOCYTES.
Preferred term Chemokine CCL18
Entry term(s) AMAC 1 Protein
AMAC-1 Protein
CCL18, Chemokine
MIP 4 Protein
MIP-4 Protein
Macrophage Inflammatory Protein 4
Pulmonary and Activation Regulated Chemokine
Pulmonary and Activation-Regulated Chemokine



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