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Descriptor English: Phosphotyrosine
Descriptor Spanish: Fosfotirosina
Descriptor fosfotirosina
Scope note: Aminoácido que se da en las proteínas endógenas. La fosforilación y la desfosforilación de la tirosina desempeñan un papel en la transducción de señales celulares y posiblemente en el control del crecimiento celular y en la carcinogénesis.
Descriptor Portuguese: Fosfotirosina
Descriptor French: Phosphotyrosine
Entry term(s): Tyrosine O phosphate
Tyrosine-O-phosphate
Tree number(s): D12.125.072.050.875.750
D12.125.740.740
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019000
Scope note: An amino acid that occurs in endogenous proteins. Tyrosine phosphorylation and dephosphorylation plays a role in cellular signal transduction and possibly in cell growth control and carcinogenesis.
Annotation: an amino acid; /biosyn /drug eff /physiol permitted
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Registry Number: 21820-51-9
CAS Type 1 Name: L-tyrosine, dihydrogen phosphate (ester)
Previous Indexing: Tyrosine/analogs & derivatives (1980-1995)
Public MeSH Note: 96; PHOSPHOTYROSINE was indexed under TYROSINE/analogs & derivatives 1980-95
Online Note: use PHOSPHOTYROSINE (NM) to search PHOSPHOTYROSINE 1980-95
History Note: 96; was PHOSPHOTYROSINE (NM) 1980-95
DeCS ID: 32649
Unique ID: D019000
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1996/01/01
Date of Entry: 1995/06/05
Revision Date: 2001/07/25
Phosphotyrosine - Preferred
Concept UI M0028374
Scope note An amino acid that occurs in endogenous proteins. Tyrosine phosphorylation and dephosphorylation plays a role in cellular signal transduction and possibly in cell growth control and carcinogenesis.
Preferred term Phosphotyrosine
Entry term(s) Tyrosine O phosphate
Tyrosine-O-phosphate



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