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Descriptor English: Tirofiban
Descriptor Spanish: Tirofibán
Descriptor tirofibán
Entry term(s) Aggrastat
Agrastat
L 700,462
L 700462
L-700,462
L-700462
L700,462
MK 383
MK-383
N-(butilsulfonil)-O-(4-(4-piperidil)butil)-L-tirosina
clorhidrato de tirofibán
clorhidrato monohidratado de tirofibán
hidrocloruro de tirofibán
hidrocloruro monohidratado de tirofibán
Scope note: Análogo de la tirosina y antagonista del COMPLEJO GPIIB-IIIA DE GLICOPROTEÍNA PLAQUETARIA que inhibe la AGREGACIÓN PLAQUETARIA y se usa en el tratamiento del SÍNDROME CORONARIO AGUDO.
Descriptor Portuguese: Tirofibana
Descriptor French: Tirofiban
Entry term(s): Aggrastat
Agrastat
L 700,462
L 700462
L-700,462
L-700462
L700,462
MK 383
MK-383
N-(Butylsulfonyl)-O-(4-(4-piperidyl)butyl)-L-tyrosine
Tirofiban Hydrochloride
Tirofiban Hydrochloride Monohydrate
Tree number(s): D12.125.072.050.875.875
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077466
Scope note: Tyrosine analog and PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX antagonist that inhibits PLATELET AGGREGATION and is used in the treatment of ACUTE CORONARY SYNDROME.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Fibrinolytic Agents
Platelet Aggregation Inhibitors
Registry Number: GGX234SI5H
Public MeSH Note: 2019; TIROFIBAN was indexed under TYROSINE/analogs&derivatives 1993-2018
History Note: 2019 (1993)
DeCS ID: 57654
Unique ID: D000077466
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/07/03
Tirofiban - Preferred
Concept UI M0211213
Scope note Tyrosine analog and PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX antagonist that inhibits PLATELET AGGREGATION and is used in the treatment of ACUTE CORONARY SYNDROME.
Preferred term Tirofiban
Entry term(s) N-(Butylsulfonyl)-O-(4-(4-piperidyl)butyl)-L-tyrosine
Aggrastat - Narrower
Concept UI M0211206
Preferred term Aggrastat
Agrastat - Narrower
Concept UI M000637166
Preferred term Agrastat
MK 383 - Narrower
Concept UI M0211210
Preferred term MK 383
Entry term(s) MK-383
L 700462 - Narrower
Concept UI M0211207
Preferred term L 700462
Entry term(s) L 700,462
L-700,462
L-700462
L700,462
Tirofiban Hydrochloride - Narrower
Concept UI M0326022
Preferred term Tirofiban Hydrochloride
Tirofiban Hydrochloride Monohydrate - Narrower
Concept UI M000637167
Preferred term Tirofiban Hydrochloride Monohydrate



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