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Descriptor English: Arrestin
Descriptor Spanish: Arrestina
Descriptor arrestina
Entry term(s) antígeno S retiniano
antígeno retiniano S
Scope note: Proteína de 48-kDa del segmento externo de los bastones retinianos y componente de la cascada fototransductora. La arrestina interrumpe la activación de la proteína G mediante su unión a la rodopsina fotolizada fosforilada. La arrestina causa uveítis autoinmune experimental.
Descriptor Portuguese: Arrestina
Descriptor French: Arrestine
Entry term(s): Retinal S Antigen
Retinal S-Antigen
S Antigen, Retinal
S-Antigen, Retinal
Tree number(s): D12.644.360.024.098.050
D12.776.157.057.005.050
D12.776.306.090.050
D12.776.476.024.104.050
D12.776.543.090.050
D23.050.301.280
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019393
Scope note: A 48-Kd protein of the outer segment of the retinal rods and a component of the phototransduction cascade. Arrestin quenches G-protein activation by binding to phosphorylated photolyzed rhodopsin. Arrestin causes experimental autoimmune uveitis when injected into laboratory animals.
Annotation: an eye protein; do not confuse with ARRESTINS
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Antigens (1981-1996)
Eye Proteins (1983-1996)
Public MeSH Note: 97; S ANTIGEN, RETINAL was indexed under ANTIGENS & EYE PROTEINS 1981-96
Online Note: use ARRESTIN (NM) to search S ANTIGEN, RETINAL 1981-96
History Note: 97; was S ANTIGEN, RETINAL (NM) 1981-96
DeCS ID: 33049
Unique ID: D019393
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1997/01/01
Date of Entry: 1996/06/10
Revision Date: 2016/04/18
Arrestin - Preferred
Concept UI M0028858
Scope note A 48-Kd protein of the outer segment of the retinal rods and a component of the phototransduction cascade. Arrestin quenches G-protein activation by binding to phosphorylated photolyzed rhodopsin. Arrestin causes experimental autoimmune uveitis when injected into laboratory animals.
Preferred term Arrestin
Entry term(s) Retinal S Antigen
Retinal S-Antigen
S Antigen, Retinal
S-Antigen, Retinal



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