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Descriptor English: Variant Surface Glycoproteins, Trypanosoma
Descriptor Spanish: Glicoproteínas Variantes de Superficie de Trypanosoma
Descriptor glicoproteínas variantes de superficie del tripanosoma
Entry term(s) glicoproteínas variantes de la cubierta superficial del tripanosoma
Scope note: Glicoproteínas unidas a la cubierta de la superficie del tripanosoma. Muchas de las glicoproteínas muestran diversas secuencias de aminoácidos expresados como variaciones antigénicas. Este desarrollo contínuo de variantes antigénicamente diferentes en el curso de la infección asegura que algunos tripanosomas siempre sobrevivan al desarrollo de la respuesta inmune, para propagar la infección.
Descriptor Portuguese: Glicoproteínas Variantes de Superfície de Trypanosoma
Descriptor French: Glycoprotéines de surface variables du trypanosome
Entry term(s): SSP-4
Surface Variant Glycoproteins, Trypanosoma
Trypanosoma Variant Surface Coat Glycoproteins
VSG 117
VSG 118
VSG 221
Tree number(s): D09.400.430.890.990
D12.776.395.550.990
D12.776.543.550.990
D12.776.820.125.900
D23.050.293.900
D23.050.301.900
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D014643
Scope note: Glycoproteins attached to the surface coat of the trypanosome. Many of these glycoproteins show amino acid sequence diversity expressed as antigenic variations. This continuous development of antigenically distinct variants in the course of infection ensures that some trypanosomes always survive the development of immune response to propagate the infection.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PO poisoning
RE radiation effects
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Glycoproteins (1966-1987)
Membrane Proteins (1977-1987)
Public MeSH Note: 88
History Note: 88
Entry Version: VSG TRYPAN
DeCS ID: 27897
Unique ID: D014643
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1988/01/01
Date of Entry: 1987/05/05
Revision Date: 2005/06/30
Variant Surface Glycoproteins, Trypanosoma - Preferred
Concept UI M0022522
Scope note Glycoproteins attached to the surface coat of the trypanosome. Many of these glycoproteins show amino acid sequence diversity expressed as antigenic variations. This continuous development of antigenically distinct variants in the course of infection ensures that some trypanosomes always survive the development of immune response to propagate the infection.
Preferred term Variant Surface Glycoproteins, Trypanosoma
Entry term(s) SSP-4
Surface Variant Glycoproteins, Trypanosoma
Trypanosoma Variant Surface Coat Glycoproteins
VSG 117 - Narrower
Concept UI M0022523
Preferred term VSG 117
VSG 221 - Narrower
Concept UI M0022525
Preferred term VSG 221
VSG 118 - Narrower
Concept UI M0022524
Preferred term VSG 118



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