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Descriptor in English: Macrophage Inflammatory Proteins
Descriptor in Spanish: Proteínas Inflamatorias de Macrófagos
Descriptor in Portuguese: Proteínas Inflamatórias de Macrófagos
Descriptor in French: Protéines inflammatoires des macrophages
Entry term(s): Inflammatory Proteins, Macrophage
Macrophage Inflammatory Protein-1
Tree number(s): D12.644.276.374.200.600
D12.776.467.374.200.600
D23.125.300.600
D23.469.200.600
D23.529.374.200.600
Scope note: Heparin-binding proteins that exhibit a number of inflammatory and immunoregulatory activities. Originally identified as secretory products of MACROPHAGES, these chemokines are produced by a variety of cell types including NEUTROPHILS; FIBROBLASTS; and EPITHELIAL CELLS. They likely play a significant role in respiratory tract defenses.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
History Note: 1997
DeCS UI: 33073
Descriptor UI: D019402
Date Established: 1997/01/01
Date of Entry: 1996/06/10
Revision Date: 2009/08/19
Macrophage Inflammatory Proteins - Preferred
Concept UI M0028870
Scope note Heparin-binding proteins that exhibit a number of inflammatory and immunoregulatory activities. Originally identified as secretory products of MACROPHAGES, these chemokines are produced by a variety of cell types including NEUTROPHILS; FIBROBLASTS; and EPITHELIAL CELLS. They likely play a significant role in respiratory tract defenses.
Preferred term Macrophage Inflammatory Proteins
Entry term(s) Inflammatory Proteins, Macrophage
Macrophage Inflammatory Protein-1 - Narrower
Concept UI M0522815
Preferred term Macrophage Inflammatory Protein-1



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