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Descriptor English: Genes, bcl-2
Descriptor Spanish: Genes bcl-2
Descriptor genes bcl-2
Entry term(s) genes c-bcl-2
Scope note: Son los genes 2 de la leucemia/linfoma B responsables del bloqueo de la apoptosis en las células normales cuya sobreexpresión se asocia a linfoma folicular. La sobreexpresión es consecuencia de la translocación t(14;18). El gen humano c-bcl-2 está localizado en la región 18q24 del brazo largo del cromosoma 18.
Descriptor Portuguese: Genes bcl-2
Descriptor French: Gènes bcl-2
Entry term(s): Gene, bcl-2
Gene, c-bcl-2
Genes, bcl 2
Genes, c-bcl-2
Proto-Oncogene, c-bcl-2
Proto-Oncogenes, c-bcl-2
bcl 2 Genes
bcl-2 Gene
bcl-2 Genes
c bcl 2 Genes
c bcl 2 Proto Oncogenes
c-bcl-2 Gene
c-bcl-2 Genes
c-bcl-2 Proto-Oncogene
c-bcl-2 Proto-Oncogenes
Tree number(s): G05.360.340.024.340.375.500.791.150
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019254
Scope note: The B-cell leukemia/lymphoma-2 genes, responsible for blocking apoptosis in normal cells, and associated with follicular lymphoma when overexpressed. Overexpression results from the t(14;18) translocation. The human c-bcl-2 gene is located at 18q24 on the long arm of chromosome 18.
Annotation: bcl stands for "B-Cell Leukemia"
Allowable Qualifiers: DE drug effects
ES ethics
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Oncogenes (1984-1996)
Proto-Oncogenes (1988-1996)
Public MeSH Note: 97
History Note: 97
Related: Proto-Oncogene Proteins c-bcl-2 MeSH
DeCS ID: 33162
Unique ID: D019254
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1997/01/01
Date of Entry: 1996/06/13
Revision Date: 2008/07/08
Genes, bcl-2 - Preferred
Concept UI M0028675
Scope note The B-cell leukemia/lymphoma-2 genes, responsible for blocking apoptosis in normal cells, and associated with follicular lymphoma when overexpressed. Overexpression results from the t(14;18) translocation. The human c-bcl-2 gene is located at 18q24 on the long arm of chromosome 18.
Preferred term Genes, bcl-2
Entry term(s) Gene, bcl-2
Genes, bcl 2
bcl 2 Genes
bcl-2 Gene
bcl-2 Genes
c-bcl-2 Genes - Narrower
Concept UI M0028674
Preferred term c-bcl-2 Genes
Entry term(s) Gene, c-bcl-2
Genes, c-bcl-2
Proto-Oncogene, c-bcl-2
Proto-Oncogenes, c-bcl-2
c bcl 2 Genes
c bcl 2 Proto Oncogenes
c-bcl-2 Gene
c-bcl-2 Proto-Oncogene
c-bcl-2 Proto-Oncogenes



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