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Descriptor English: Genes, erbA
Descriptor Spanish: Genes erbA
Descriptor genes erbA
Entry term(s) genes TR-alfa
genes TR-beta
genes c-erbA
genes erbA-alfa
genes v-erbA
Scope note: Genes relacionados con la secuencia erbA del ADN, aislada inicialmente del virus de la eritroblastosis aviar (VIRUS DE LA ERITROBLASTOSIS AVIAR), v-erbA. En las células, los genes erbA codifican los receptores de hormona tiroidea (RECEPTORES DE HORMONA TIROIDEA). Se han identificado dos genes c-erbA diferentes: erbA-alfa localizado en 17q21 y erbA-beta localizado en 3p24. Los truncamientos en el N- y C-terminales de erbA dan lugar a productos similares a v-erbA. Los truncamientos afectan a la respuesta a la hormona pero no a la capacidad de unión del ADN.
Descriptor Portuguese: Genes erbA
Descriptor French: Gènes erbA
Entry term(s): Gene, THRA
Gene, THRB
Genes, THRA
Genes, THRB
Genes, TR alpha
Genes, TR beta
Genes, TR-alpha
Genes, TR-beta
Genes, erbA alpha
Genes, erbA beta
Genes, erbA-alpha
Genes, erbA-beta
THRA Gene
THRA Genes
THRB Gene
THRB Genes
TR alpha Gene
TR alpha Genes
TR beta Gene
TR beta Genes
TR-alpha Gene
TR-alpha Genes
TR-beta Gene
TR-beta Genes
alpha Gene, TR
alpha Gene, erbA
alpha Genes, TR
alpha Genes, erbA
beta Gene, TR
beta Gene, erbA
beta Genes, TR
beta Genes, erbA
c erbA Genes
c erbA Proto Oncogenes
c-erbA Gene
c-erbA Genes
c-erbA Proto-Oncogene
c-erbA Proto-Oncogenes
erbA Gene
erbA Genes
erbA alpha Gene
erbA alpha Genes
erbA beta Gene
erbA beta Genes
erbA-alpha Gene
erbA-alpha Genes
erbA-beta Gene
erbA-beta Genes
v erbA Genes
v erbA Oncogenes
v-erbA Gene
v-erbA Genes
v-erbA Oncogene
v-erbA Oncogenes
Tree number(s): G05.360.340.024.340.375.500.791.290
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D018776
Scope note: Genes related to the erbA DNA sequence that was first isolated from the avian erythroblastosis virus (ERYTHROBLASTOSIS VIRUS, AVIAN), v-erbA. In cells, erbA genes encode thyroid hormone receptors (RECEPTORS, THYROID HORMONE). Two distinct c-erbA genes have been identified: erbA-alpha located at 17q21; and erbA-beta located at 3p24. Truncations at the N- and C-terminals of erbA result in products resembling v-erbA. Truncations affect hormone responsiveness but not DNA binding capacity.
Annotation: erbA stands for "ERythroBlastosis virus, Avian"; GENES, ERBB & its specifics are also available; in titles & translations spell as erbA
Allowable Qualifiers: DE drug effects
ES ethics
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Oncogenes (1984-1994)
Proto-Oncogenes (1987-1994)
Public MeSH Note: 95
History Note: 95
Related: Oncogene Proteins v-erbA MeSH
Receptors, Thyroid Hormone MeSH
DeCS ID: 32229
Unique ID: D018776
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1995/01/01
Date of Entry: 1994/05/23
Revision Date: 2008/07/08
Genes, erbA - Preferred
Concept UI M0028111
Scope note Genes related to the erbA DNA sequence that was first isolated from the avian erythroblastosis virus (ERYTHROBLASTOSIS VIRUS, AVIAN), v-erbA. In cells, erbA genes encode thyroid hormone receptors (RECEPTORS, THYROID HORMONE). Two distinct c-erbA genes have been identified: erbA-alpha located at 17q21; and erbA-beta located at 3p24. Truncations at the N- and C-terminals of erbA result in products resembling v-erbA. Truncations affect hormone responsiveness but not DNA binding capacity.
Preferred term Genes, erbA
Entry term(s) erbA Gene
erbA Genes
Genes, erbA-beta - Narrower
Concept UI M0028108
Preferred term Genes, erbA-beta
Entry term(s) Gene, THRB
Genes, THRB
Genes, TR beta
Genes, TR-beta
Genes, erbA beta
THRB Gene
THRB Genes
TR beta Gene
TR beta Genes
TR-beta Gene
TR-beta Genes
beta Gene, TR
beta Gene, erbA
beta Genes, TR
beta Genes, erbA
erbA beta Gene
erbA beta Genes
erbA-beta Gene
erbA-beta Genes
Genes, erbA-alpha - Narrower
Concept UI M0028107
Preferred term Genes, erbA-alpha
Entry term(s) Gene, THRA
Genes, THRA
Genes, TR alpha
Genes, TR-alpha
Genes, erbA alpha
THRA Gene
THRA Genes
TR alpha Gene
TR alpha Genes
TR-alpha Gene
TR-alpha Genes
alpha Gene, TR
alpha Gene, erbA
alpha Genes, TR
alpha Genes, erbA
erbA alpha Gene
erbA alpha Genes
erbA-alpha Gene
erbA-alpha Genes
v-erbA Genes - Narrower
Concept UI M0028110
Scope note Viral oncogenes that are homologues of erbA1 (THRA) gene which encodes thyroid hormone receptor alpha. v-erbA Oncogenes potentiate the transforming ability of other oncogenes such as v-erbB by inhibiting spontaneous differentiation of already transformed cells.
Preferred term v-erbA Genes
Entry term(s) v erbA Genes
v erbA Oncogenes
v-erbA Gene
v-erbA Oncogene
v-erbA Oncogenes
c-erbA Genes - Narrower
Concept UI M0028109
Preferred term c-erbA Genes
Entry term(s) c erbA Genes
c erbA Proto Oncogenes
c-erbA Gene
c-erbA Proto-Oncogene
c-erbA Proto-Oncogenes



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