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Descriptor English: O(6)-Methylguanine-DNA Methyltransferase
Descriptor Spanish: O(6)-Metilguanina-ADN Metiltransferasa
Descriptor O(6)-metilguanina-ADN metiltransferasa
Entry term(s) ADN-proteína-cisteína metilado S-metiltransferasa
O(6)-AGT
O(6)-metilguanina metiltransferasa
Scope note: Enzima que transfiere a un residuo de cisteína propio grupos metilo de la O(6)-metilguanina y otras partes metiladas del ADN, reparando de ese modo el ADN alquilado en una reacción de una única etapa. EC 2.1.1.63.
Descriptor Portuguese: O(6)-Metilguanina-DNA Metiltransferase
Descriptor French: O(6)-methylguanine-DNA methyltransferase
Entry term(s): DNA Repair Methyltransferase I
DNA Repair Methyltransferase II
Guanine-O(6)-Alkyltransferase
Methylated DNA Protein Cysteine S Methyltransferase
Methylated-DNA-Protein-Cysteine S-Methyltransferase
O(6)-AGT
O(6)-Alkylguanine-DNA Alkyltransferase
O(6)-MeG-DNA Methyltransferase
O(6)-Methylguanine DNA Transmethylase
O(6)-Methylguanine Methyltransferase
S-Methyltransferase, Methylated-DNA-Protein-Cysteine
Tree number(s): D08.811.913.555.500.800.650
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019853
Scope note: An enzyme that transfers methyl groups from O(6)-methylguanine, and other methylated moieties of DNA, to a cysteine residue in itself, thus repairing alkylated DNA in a single-step reaction. EC 2.1.1.63.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.1.1.63
CAS Type 1 Name: DNA-6-O-methylguanine:protein-L-cysteine S-methyltransferase
Previous Indexing: DNA (Cytosine-5-)-Methyltransferase (1978-1982)
Methyltransferases (1978-1997)
Public MeSH Note: 98; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE was indexed under METHYLTRANSFERASES 1978-97 & DNA (CYTOSINE-5-)-METHYLTRANSFERASE 1978-82
History Note: 98; use O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE (NM) 1980-97
DeCS ID: 33461
Unique ID: D019853
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1998/01/01
Date of Entry: 1997/06/20
Revision Date: 2004/07/29
O(6)-Methylguanine-DNA Methyltransferase - Preferred
Concept UI M0029471
Scope note An enzyme that transfers methyl groups from O(6)-methylguanine, and other methylated moieties of DNA, to a cysteine residue in itself, thus repairing alkylated DNA in a single-step reaction. EC 2.1.1.63.
Preferred term O(6)-Methylguanine-DNA Methyltransferase
Entry term(s) Guanine-O(6)-Alkyltransferase
Methylated DNA Protein Cysteine S Methyltransferase
Methylated-DNA-Protein-Cysteine S-Methyltransferase
O(6)-AGT
O(6)-Alkylguanine-DNA Alkyltransferase
O(6)-MeG-DNA Methyltransferase
O(6)-Methylguanine DNA Transmethylase
O(6)-Methylguanine Methyltransferase
S-Methyltransferase, Methylated-DNA-Protein-Cysteine
DNA Repair Methyltransferase II - Narrower
Concept UI M0029473
Preferred term DNA Repair Methyltransferase II
DNA Repair Methyltransferase I - Narrower
Concept UI M0029472
Preferred term DNA Repair Methyltransferase I



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