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Descriptor English: Proto-Oncogene Proteins c-raf
Descriptor Spanish: Proteínas Proto-Oncogénicas c-raf
Descriptor proteínas protooncogénicas c-raf
Entry term(s) proteínas c-raf
proteínas de protooncogén c-raf
proteínas del protooncogén c-raf
Scope note: Subclase de cinasa raf de expresión ubicua que desempeña un importante papel en la TRANSDUCCIÓN DE SEÑALES. Las cinasas c-raf son MAP cinasa cinasa cinasas que tienen especificidad por MAP CINASA CINASA 1 y MAP CINASA CINASA 2.
Descriptor Portuguese: Proteínas Proto-Oncogênicas c-raf
Descriptor French: Protéines proto-oncogènes c-raf
Entry term(s): Kinase Raf 1
Kinase Raf-1
Kinase p74(raf-1)
Kinase, cRaf1
Kinase, raf-1
Kinases, c-raf
Protein c-raf, Proto-Oncogene
Proteins c-raf, Proto-Oncogene
Proteins, c-raf
Proto Oncogene Protein c raf
Proto Oncogene Proteins c raf
Proto-Oncogene Protein c-raf
Raf-1, Kinase
c raf Kinases
c raf Proteins
c-raf Kinases
c-raf Proteins
c-raf, Proto-Oncogene Protein
c-raf, Proto-Oncogene Proteins
cRaf1 Kinase
raf 1 Kinase
raf-1 Kinase
Tree number(s): D08.811.913.696.620.682.700.559.842.500
D12.776.476.563.554.842.500
D12.776.624.664.700.204.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019908
Scope note: A ubiquitously expressed raf kinase subclass that plays an important role in SIGNAL TRANSDUCTION. The c-raf Kinases are MAP kinase kinase kinases that have specificity for MAP KINASE KINASE 1 and MAP KINASE KINASE 2.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.7.11.1
Previous Indexing: Protein-Serine-Threonine Kinases (1993-1997)
Proto-Oncogene Proteins (1986-1997)
Public MeSH Note: 1998; PROTO-ONCOGENE PROTEIN MIL (now PROTO-ONCOGENE PROTEINS C-RAF) was indexed under PROTEIN-SERINE-THEONINE KINASES 1993-1997 & PROTO-ONCOGENE PROTEINS 1986-1997; CRAF1 KINASE was indexed under PROTO-ONCOGENE PROTEINS C-RAF 1993-2004
History Note: 1998 (1986)
Related: Oncogene Proteins v-raf MeSH
DeCS ID: 33473
Unique ID: D019908
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1998/01/01
Date of Entry: 1997/06/20
Revision Date: 2015/11/24
Proto-Oncogene Proteins c-raf - Preferred
Concept UI M0029578
Scope note A ubiquitously expressed raf kinase subclass that plays an important role in SIGNAL TRANSDUCTION. The c-raf Kinases are MAP kinase kinase kinases that have specificity for MAP KINASE KINASE 1 and MAP KINASE KINASE 2.
Preferred term Proto-Oncogene Proteins c-raf
Entry term(s) Kinase Raf 1
Kinase Raf-1
Kinase p74(raf-1)
Kinase, cRaf1
Kinase, raf-1
Kinases, c-raf
Protein c-raf, Proto-Oncogene
Proteins c-raf, Proto-Oncogene
Proteins, c-raf
Proto Oncogene Protein c raf
Proto Oncogene Proteins c raf
Proto-Oncogene Protein c-raf
Raf-1, Kinase
c raf Kinases
c raf Proteins
c-raf Kinases
c-raf Proteins
c-raf, Proto-Oncogene Protein
c-raf, Proto-Oncogene Proteins
cRaf1 Kinase
raf 1 Kinase
raf-1 Kinase



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