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Descriptor English: Locus Control Region
Descriptor Spanish: Región de Control de Posición
Descriptor región de control de locus
Entry term(s) región de control del locus
Scope note: Región reguladora que fue identificada por primera vez en el locus de la globina beta humana pero que se halló posteriormente en otros loci. Se piensa que la región regula la TRANSCRIPCIÓN GENÉTICA mediante la apertura y remodelación de la estructura de la CROMATINA. También puede tener actividad facilitadora.
Descriptor Portuguese: Região de Controle de Locus Gênico
Descriptor French: Région de contrôle de locus
Entry term(s): Control Region, Locus
Control Regions, Locus
Locus Control Regions
Region, Locus Control
Regions, Locus Control
Tree number(s): G02.111.570.080.689.450
G05.360.080.689.450
G05.360.340.024.380.249
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019901
Scope note: A regulatory region first identified in the human beta-globin locus but subsequently found in other loci. The region is believed to regulate GENETIC TRANSCRIPTION by opening and remodeling CHROMATIN structure. It may also have enhancer activity.
Allowable Qualifiers: DE drug effects
ES ethics
GE genetics
IM immunology
PH physiology
RE radiation effects
Public MeSH Note: 98
History Note: 98
DeCS ID: 33600
Unique ID: D019901
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1998/01/01
Date of Entry: 1997/06/20
Revision Date: 2009/07/14
Locus Control Region - Preferred
Concept UI M0029559
Scope note A regulatory region first identified in the human beta-globin locus but subsequently found in other loci. The region is believed to regulate GENETIC TRANSCRIPTION by opening and remodeling CHROMATIN structure. It may also have enhancer activity.
Preferred term Locus Control Region
Entry term(s) Control Region, Locus
Control Regions, Locus
Locus Control Regions
Region, Locus Control
Regions, Locus Control



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