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Descriptor English: Acquired Hyperostosis Syndrome
Descriptor Spanish: Síndrome de Hiperostosis Adquirido
Descriptor Portuguese: Síndrome de Hiperostose Adquirida
Descriptor French: Syndrome SAPHO
Entry term(s): Acquired Hyperostosis Syndromes
Hyperostosis Syndrome, Acquired
Hyperostosis Syndromes, Acquired
SAPHO Syndrome
SAPHO Syndromes
Syndrome, Acquired Hyperostosis
Syndrome, SAPHO
Syndromes, Acquired Hyperostosis
Syndromes, SAPHO
Synovitis, Acne, Pustlosis, Hyperostosis, and Osteomyelitis
Tree number(s): C05.116.099.708.025
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020083
Scope note: Syndrome consisting of SYNOVITIS; ACNE CONGLOBATA; PALMOPLANTAR PUSTULOSIS; HYPEROSTOSIS; and OSTEITIS. The most common site of the disease is the upper anterior chest wall, characterized by predominantly osteosclerotic lesions, hyperostosis, and arthritis of the adjacent joints. The association of sterile inflammatory bone lesions and neutrophilic skin eruptions is indicative of this syndrome.
Allowable Qualifiers: BL blood
CF cerebrospinal fluid
CI chemically induced
CL classification
CN congenital
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SU surgery
TH therapy
UR urine
VE veterinary
VI virology
Public MeSH Note: 99
History Note: 99
DeCS ID: 33757
Unique ID: D020083
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1999/01/01
Date of Entry: 1998/06/10
Revision Date: 2015/06/22
Acquired Hyperostosis Syndrome - Preferred
Concept UI M0029804
Scope note Syndrome consisting of SYNOVITIS; ACNE CONGLOBATA; PALMOPLANTAR PUSTULOSIS; HYPEROSTOSIS; and OSTEITIS. The most common site of the disease is the upper anterior chest wall, characterized by predominantly osteosclerotic lesions, hyperostosis, and arthritis of the adjacent joints. The association of sterile inflammatory bone lesions and neutrophilic skin eruptions is indicative of this syndrome.
Preferred term Acquired Hyperostosis Syndrome
Entry term(s) Acquired Hyperostosis Syndromes
Hyperostosis Syndrome, Acquired
Hyperostosis Syndromes, Acquired
SAPHO Syndrome
SAPHO Syndromes
Syndrome, Acquired Hyperostosis
Syndrome, SAPHO
Syndromes, Acquired Hyperostosis
Syndromes, SAPHO
Synovitis, Acne, Pustlosis, Hyperostosis, and Osteomyelitis



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