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Descriptor English: Serotonin Syndrome
Descriptor Spanish: Síndrome de la Serotonina
Descriptor síndrome de la serotonina
Scope note: Interacción adversa a medicamentos que se caracterizan por estado mental alterado, disfunción del sistema nervioso autónomo, y anomalías neuromusculares. Se producen con mayor frecuencia por el uso de inhibidores de la captación de serotonina e inhibidores de la monoaminoxidasa, lo que produce un exceso de la serotonina disponible en los receptores 1A de serotonina del SNC.
Descriptor Portuguese: Síndrome da Serotonina
Descriptor French: Syndrome sérotoninergique
Entry term(s): Serotonin Syndromes
Syndrome, Serotonin
Syndromes, Serotonin
Tree number(s): C25.100.875
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020230
Scope note: An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.
Allowable Qualifiers: BL blood
CF cerebrospinal fluid
CI chemically induced
CL classification
CN congenital
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SU surgery
TH therapy
UR urine
VE veterinary
VI virology
Previous Indexing: Serotonin (1980-1992)
Serotonin Uptake Inhibitors/adverse effects (1993-1998)
Public MeSH Note: 99
History Note: 99
Related: Monoamine Oxidase Inhibitors MeSH
Serotonin MeSH
Serotonin Uptake Inhibitors MeSH
DeCS ID: 33777
Unique ID: D020230
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1999/01/01
Date of Entry: 1998/06/11
Revision Date: 2013/07/08
Serotonin Syndrome - Preferred
Concept UI M0029903
Scope note An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.
Preferred term Serotonin Syndrome
Entry term(s) Serotonin Syndromes
Syndrome, Serotonin
Syndromes, Serotonin



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