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Descriptor English: Milrinone
Descriptor Spanish: Milrinona
Descriptor milrinona
Scope note: Agente cardiotónico inotrópico positivo con propiedades vasodilatadoras. Inhibe la actividad de la fosfodiesterasa de AMPc en el miocardio y en el músculo liso vascular. La milrinona es un derivado de la amrinona y posee 20-30 veces mas potencia inotrópica que la amrinona.
Descriptor Portuguese: Milrinona
Descriptor French: Milrinone
Entry term(s): Corotrop
Corotrope
Lactate, Milrinone
Milrinone Lactate
Primacor
Win 47203
Win-47203
Win47203
Tree number(s): D02.092.080.085.543
D03.383.725.050.085.543
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020105
Scope note: A positive inotropic cardiotonic agent with vasodilator properties. It inhibits cAMP phosphodiesterase type 3 activity in myocardium and vascular smooth muscle. Milrinone is a derivative of amrinone and has 20-30 times the inotropic potency of amrinone.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Cardiotonic Agents
Platelet Aggregation Inhibitors
Vasodilator Agents
Phosphodiesterase 3 Inhibitors
Registry Number: JU9YAX04C7
CAS Type 1 Name: (3,4'-Bipyridine)-5-carbonitrile, 6-dihydro-2-methyl-6-oxo-
Previous Indexing: Pyridones (1983-1998)
Public MeSH Note: 99; MILRINONE was indexed under PYRIDONES 1983-98
History Note: 99; use MILRINONE (NM) 1983-98
DeCS ID: 33788
Unique ID: D020105
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1999/01/01
Date of Entry: 1998/06/10
Revision Date: 2017/05/24
Milrinone - Preferred
Concept UI M0029839
Scope note A positive inotropic cardiotonic agent with vasodilator properties. It inhibits cAMP phosphodiesterase type 3 activity in myocardium and vascular smooth muscle. Milrinone is a derivative of amrinone and has 20-30 times the inotropic potency of amrinone.
Preferred term Milrinone
Win-47203 - Narrower
Concept UI M0350974
Preferred term Win-47203
Entry term(s) Win 47203
Win47203
Primacor - Narrower
Concept UI M0029841
Preferred term Primacor
Corotrope - Narrower
Concept UI M0474337
Preferred term Corotrope
Entry term(s) Corotrop
Milrinone Lactate - Narrower
Concept UI M0029840
Preferred term Milrinone Lactate
Entry term(s) Lactate, Milrinone



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