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Descriptor English: Amrinone
Descriptor Spanish: Amrinona
Descriptor amrinona
Scope note: Cardiotónico inotropo positivo (AGENTES CARDIOTÓNICOS) con propiedades vasodilatadoras, actividad inhibidora de fosfodiesterasa y capacidad para estimular la entrada de calcio en la célula cardiaca.
Descriptor Portuguese: Amrinona
Descriptor French: Amrinone
Entry term(s): 5-Amino-(3,4'-bipyridine)-6(1H)-one
Amrinon
Cordemcura
Inocor
Win 40680
Win-40680
Win40680
Wincoram
Tree number(s): D02.092.080.085
D03.383.725.050.085
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000676
Scope note: A positive inotropic cardiotonic (CARDIOTONIC AGENTS) with vasodilator properties, phosphodiesterase 3 inhibitory activity, and the ability to stimulate calcium ion influx into the cardiac cell.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Calcium Channel Blockers
Cardiotonic Agents
Vasodilator Agents
Phosphodiesterase 3 Inhibitors
Registry Number: JUT23379TN
CAS Type 1 Name: (3,4'-Bipyridin)-6(1H)-one, 5-amino-
Previous Indexing: Aminopyridines (1979-1986)
Pyridines (1966-1978)
Public MeSH Note: 87
History Note: 87
DeCS ID: 23219
Unique ID: D000676
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1987/01/01
Date of Entry: 1986/06/16
Revision Date: 2017/05/24
Amrinone - Preferred
Concept UI M0001038
Scope note A positive inotropic cardiotonic (CARDIOTONIC AGENTS) with vasodilator properties, phosphodiesterase 3 inhibitory activity, and the ability to stimulate calcium ion influx into the cardiac cell.
Preferred term Amrinone
Entry term(s) 5-Amino-(3,4'-bipyridine)-6(1H)-one
Amrinon
Wincoram - Narrower
Concept UI M0372291
Preferred term Wincoram
Win-40680 - Narrower
Concept UI M0372293
Preferred term Win-40680
Entry term(s) Win 40680
Win40680
Cordemcura - Narrower
Concept UI M0433452
Preferred term Cordemcura
Inocor - Narrower
Concept UI M0372292
Preferred term Inocor



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