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Descriptor English: Cotinine
Descriptor Spanish: Cotinina
Descriptor cotinina
Scope note: El conjugado N-glucurónido de la cotinina, que es el principal metabolito urinario de la NICOTINA. Sirve como marcador biológico del HÁBITO DE FUMAR. Posee propiedades estimulantes del SNC.
Descriptor Portuguese: Cotinina
Descriptor French: Cotinine
Entry term(s): Scotine
Tree number(s): D03.383.773.812.180
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D003367
Scope note: The N-glucuronide conjugate of cotinine is a major urinary metabolite of NICOTINE. It thus serves as a biomarker of exposure to tobacco SMOKING. It has CNS stimulating properties.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Indicators and Reagents
Registry Number: K5161X06LL
CAS Type 1 Name: 2-Pyrrolidinone, 1-methyl-5-(3-pyridinyl)-, (S)-
Previous Indexing: Pyridines (1974)
Pyrrolidinones (1969-1974)
Public MeSH Note: 91; was see under PYRROLIDINONES 1975-90
History Note: 91(75); was see under PYRROLIDINONES 1975-90
DeCS ID: 3382
Unique ID: D003367
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2016/05/28
Cotinine - Preferred
Concept UI M0005249
Scope note The N-glucuronide conjugate of cotinine is a major urinary metabolite of NICOTINE. It thus serves as a biomarker of exposure to tobacco SMOKING. It has CNS stimulating properties.
Preferred term Cotinine
Entry term(s) Scotine



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