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Descriptor English: Tenuazonic Acid
Descriptor Spanish: Ácido Tenuazónico
Descriptor ácido tenuazónico
Scope note: 3-acetil-5-sec-butil-4-hidroxi-3-pirrolin-2-ona. Metabolito encontrado en una cepa del hongo Alternaria tenuis Auct. que actúa como un antibiótico con propiedades antivirales y antineoplásicas y puede también actuar como una micotoxina.
Descriptor Portuguese: Ácido Tenuazônico
Descriptor French: Acide ténuazonique
Entry term(s): Acid, Tenuazonic
Tree number(s): D03.383.773.812.900
D23.946.587.915
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013720
Scope note: 3-Acetyl-5-sec-butyl-4-hydroxy-3-pyrrolin-2-one. A metabolite found in a strain of the fungus Alternaria tenuis Auct. which functions as an antibiotic with antiviral and antineoplastic properties, and may also act as a mycotoxin.
Annotation: an antineoplastic antibiotic
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antibiotics, Antineoplastic
Antiviral Agents
Registry Number: 610-88-8
CAS Type 1 Name: 2H-Pyrrol-2-one, 3-acetyl-1,5-dihydro-4-hydroxy-5-(1-methylpropyl)-, (S-(R*,R*))-
Previous Indexing: Pyrrolidinones (1971-1974)
Public MeSH Note: 91; was see under ANTIBIOTICS, ANTINEOPLASTIC 1975-90
History Note: 91(75); was see under ANTIBIOTICS, ANTINEOPLASTIC 1975-90
DeCS ID: 14098
Unique ID: D013720
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2016/06/01
Tenuazonic Acid - Preferred
Concept UI M0021169
Scope note 3-Acetyl-5-sec-butyl-4-hydroxy-3-pyrrolin-2-one. A metabolite found in a strain of the fungus Alternaria tenuis Auct. which functions as an antibiotic with antiviral and antineoplastic properties, and may also act as a mycotoxin.
Preferred term Tenuazonic Acid
Entry term(s) Acid, Tenuazonic



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