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Descriptor English: Striatonigral Degeneration
Descriptor Spanish: Degeneración Estriatonigral
Descriptor degeneración nigroestriada
Entry term(s) degeneración negroestriada
Scope note: Enfermedad neurodegenerativa esporádica que comienza en la mediana edad y se caracteriza clínicamente por síntomas parkinsonianos (por ejemplo, RIGIDEZ MUSCULAR, HIPOCINESIA, postura estática) e HIPOTENSIÓN. Se considera que esta afección es una variante clínica de la ATROFIA DE MÚLTIPLES SISTEMAS. Las características anatomopatológicas incluyen una pérdida importante de neuronas en la zona compacta de la SUSTANCIA NEGRA y el PUTAMEN. (Adams et al., Principles of Neurology, 6th ed, p1075-6)
Descriptor Portuguese: Degeneração Estriatonigral
Descriptor French: Dégénerescence striatonigrique
Entry term(s): Atrophies, Striatonigral
Atrophy, Striatonigral
Degeneration, Striatonigral
Striatonigral Atrophies
Striatonigral Atrophy
Striatonigral Degenerations
Tree number(s): C10.177.575.550.875
C10.228.140.079.612.800
C10.228.662.550.800
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020955
Scope note: A sporadic neurodegenerative disease with onset in middle-age characterized clinically by Parkinsonian features (e.g., MUSCLE RIGIDITY; HYPOKINESIA; stooped posture) and HYPOTENSION. This condition is considered a clinical variant of MULTIPLE SYSTEM ATROPHY. Pathologic features include a prominent loss of neurons in the zona compacta of the SUBSTANTIA NIGRA and PUTAMEN. (From Adams et al., Principles of Neurology, 6th ed, p1075-6)
Allowable Qualifiers: BL blood
CF cerebrospinal fluid
CI chemically induced
CL classification
CN congenital
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SU surgery
TH therapy
UR urine
VE veterinary
VI virology
Previous Indexing: Multiple System Atrophy (1998-1999)
Parkinson Disease (1970-1993)
Substantia Nigra (1970-1999)
Public MeSH Note: 2000; see MULTIPLE SYSTEM ATROPHY 1998-1999
History Note: 2000; use MULTIPLE SYSTEM ATROPHY 1998-1999
Related: Parkinsonian Disorders MeSH
DeCS ID: 34222
Unique ID: D020955
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2000/01/01
Date of Entry: 1999/11/04
Revision Date: 2015/06/23
Striatonigral Degeneration - Preferred
Concept UI M0029075
Scope note A sporadic neurodegenerative disease with onset in middle-age characterized clinically by Parkinsonian features (e.g., MUSCLE RIGIDITY; HYPOKINESIA; stooped posture) and HYPOTENSION. This condition is considered a clinical variant of MULTIPLE SYSTEM ATROPHY. Pathologic features include a prominent loss of neurons in the zona compacta of the SUBSTANTIA NIGRA and PUTAMEN. (From Adams et al., Principles of Neurology, 6th ed, p1075-6)
Preferred term Striatonigral Degeneration
Entry term(s) Atrophies, Striatonigral
Atrophy, Striatonigral
Degeneration, Striatonigral
Striatonigral Atrophies
Striatonigral Atrophy
Striatonigral Degenerations



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