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Descriptor English: Crush Syndrome
Descriptor Spanish: Síndrome de Aplastamiento
Descriptor síndrome de aplastamiento
Scope note: Grave manifestación sistémica del trauma y la isquemia que afecta a tejidos blandos, principalmente los músculos esqueléticos, debido a un aplastamiento intenso y prolongado. Lleva al incremento de la permeabilidad de las membranas celulares y a la liberación de potasio, enzimas, y mioglobina desde el interior de las células. La disfunción renal isquémica secundaria a la hipotensión y a la disminución del flujo renal produce necrosis tubular aguda y uremia.
Descriptor Portuguese: Síndrome de Esmagamento
Descriptor French: Syndrome d'écrasement
Entry term(s): Crush Syndromes
Syndrome, Crush
Syndromes, Crush
Tree number(s): C26.257.500
C26.797.240
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D003444
Scope note: Severe systemic manifestation of trauma and ischemia involving soft tissues, principally skeletal muscle, due to prolonged severe crushing. It leads to increased permeability of the cell membrane and to the release of potassium, enzymes, and myoglobin from within cells. Ischemic renal dysfunction secondary to hypotension and diminished renal perfusion results in acute tubular necrosis and uremia.
Allowable Qualifiers: BL blood
CF cerebrospinal fluid
CI chemically induced
CL classification
CN congenital
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SU surgery
TH therapy
UR urine
VE veterinary
VI virology
Public MeSH Note: 91; was see under SHOCK, TRAUMATIC 1979-90; was see under KIDNEY FAILURE, ACUTE 1967-78; was see under ACUTE KIDNEY FAILURE 1963-66
Online Note: use KIDNEY FAILURE, ACUTE to search CRUSH SYNDROME 1966-74
History Note: 91(75); was see under SHOCK, TRAUMATIC 1979-90; was see under KIDNEY FAILURE, ACUTE 1967-78; was see under ACUTE RENAL FAILURE 1963-66
Related: Compartment Syndromes MeSH
DeCS ID: 3461
Unique ID: D003444
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/02/26
Crush Syndrome - Preferred
Concept UI M0005369
Scope note Severe systemic manifestation of trauma and ischemia involving soft tissues, principally skeletal muscle, due to prolonged severe crushing. It leads to increased permeability of the cell membrane and to the release of potassium, enzymes, and myoglobin from within cells. Ischemic renal dysfunction secondary to hypotension and diminished renal perfusion results in acute tubular necrosis and uremia.
Preferred term Crush Syndrome
Entry term(s) Crush Syndromes
Syndrome, Crush
Syndromes, Crush



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