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Descriptor English: Fusion Regulatory Protein-1
Descriptor Spanish: Proteína-1 Reguladora de Fusión
Descriptor proteína-1 reguladora de la fusión
Entry term(s) antígeno 4F2
antígeno 4F2 humano
antígeno CD98
antígeno H4F2
antígeno de superficie celular 4F2 humano
antígeno humano de activación linfocitária 4F2
antígeno-4F2
antígenos CD98
proteína FRP-1
Scope note: Proteína heterodimérica que es un antígeno de la superficie celular asociado con la activación de los linfocitos. La caracterización inicial de esta proteína puso de manifiesto una cadena pesada identificable (ANTÍGENOS, CADENA PESADA CD98) y una cadena ligera más pequeña indeterminada. Se sabe en la actualidad que una variedad de subunidades de cadena ligera (ANTÍGENOS, CADENAS LIGERAS DE CD98) pueden dimerizarse con la cadena pesada. Dependiendo de la composición de la cadena ligera se puede encontrar una diversa serie de funciones en relación con esta proteína. Las funciones comprenden: transporte de aminoácidos de tipo L, transporte de aminoácidos de tipo y+L y regulación de la fusión celular.
Descriptor Portuguese: Proteína-1 Reguladora de Fusão
Descriptor French: Antigènes CD98
Entry term(s): 4F2 Antigen
4F2 Antigen, Human
4F2-antigen
Antigen 4F2
Antigen, CD98
Antigens, CD98
CD98 Antigen
CD98 Antigens
CD98 Transport Proteins
FRP 1 protein
FRP-1 protein
Fusion Regulatory Protein 1
H4F2 Antigen
Human 4F2 Antigen
Human 4F2 Cell Surface Antigen
Human 4F2 Cell-Surface Antigen
Human Lymphocyte Activation Antigen 4F2
Regulatory Protein-1, Fusion
Transport Proteins, CD98
Tree number(s): D12.776.157.530.200.374.750.500
D12.776.157.530.200.500.500.500
D12.776.157.530.937.313.500
D12.776.543.585.200.374.750.500
D12.776.543.585.200.500.500.500
D12.776.543.585.937.313.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D027261
Scope note: A heterodimeric protein that is a cell surface antigen associated with lymphocyte activation. The initial characterization of this protein revealed one identifiable heavy chain (FUSION REGULATORY PROTEIN 1, HEAVY CHAIN) and an indeterminate smaller light chain. It is now known that a variety of light chain subunits (FUSION REGULATORY PROTEIN 1, LIGHT CHAINS) can dimerize with the heavy chain. Depending upon its light chain composition a diverse array of functions can be found for this protein. Functions include: type L amino acid transport, type y+L amino acid transport and regulation of cellular fusion.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Antigens, CD (1996-2001)
Antigens, Surface (1989-1995)
Carrier Proteins (1996-2001)
Public MeSH Note: 2018; see ANTIGENS, CD98 1988-2017; FUSION REGULATORY PROTEIN-1 was indexed under CARRIER PROTEINS 1996-2001; under ANTIGENS CD 1996-2001; and under ANTIGENS, SURFACE 1989-1995
History Note: 2018 (1988)
DeCS ID: 36158
Unique ID: D027261
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2002/01/01
Date of Entry: 2001/07/25
Revision Date: 2017/05/24
Fusion Regulatory Protein-1 - Preferred
Concept UI M0159086
Scope note A heterodimeric protein that is a cell surface antigen associated with lymphocyte activation. The initial characterization of this protein revealed one identifiable heavy chain (FUSION REGULATORY PROTEIN 1, HEAVY CHAIN) and an indeterminate smaller light chain. It is now known that a variety of light chain subunits (FUSION REGULATORY PROTEIN 1, LIGHT CHAINS) can dimerize with the heavy chain. Depending upon its light chain composition a diverse array of functions can be found for this protein. Functions include: type L amino acid transport, type y+L amino acid transport and regulation of cellular fusion.
Preferred term Fusion Regulatory Protein-1
Entry term(s) 4F2 Antigen
4F2-antigen
Antigen 4F2
Antigen, CD98
Antigens, CD98
CD98 Antigen
CD98 Antigens
CD98 Transport Proteins
FRP 1 protein
FRP-1 protein
Fusion Regulatory Protein 1
Regulatory Protein-1, Fusion
Transport Proteins, CD98
Human 4F2 Antigen - Narrower
Concept UI M0360036
Preferred term Human 4F2 Antigen
Entry term(s) 4F2 Antigen, Human
H4F2 Antigen
Human 4F2 Cell Surface Antigen
Human 4F2 Cell-Surface Antigen
Human Lymphocyte Activation Antigen 4F2



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