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Descriptor English: Fusion Regulatory Protein 1, Heavy Chain
Descriptor Spanish: Cadena Pesada de la Proteína-1 Reguladora de Fusión
Descriptor cadena pesada de la proteína 1 reguladora de la fusión
Entry term(s) cadena pesada 4F2
cadena pesada FRP-1
cadena pesada de antígeno CD98
cadena pesada del antígeno 4F2
miembro 2 de la familia 3 de transportadores de soluto
proteína SLC3A2
subunidad 4F2HC
Scope note: Subunidad glicoproteica transmembranaria que puede dimerizarse con una variedad de subunidades de cadena ligera (CADENAS LIGERAS DE ANTÍGENOS CD98). Esta subunidad proteica atiende a un diverso conjunto de funciones que incluyen el transporte de aminoácidos y la fusión celular. Su función se ve alterada dependiendo de las subunidades de cadena ligera con las que interactúa.
Descriptor Portuguese: Cadeia Pesada da Proteína-1 Reguladora de Fusão
Descriptor French: Chaine lourde de l'antigène CD98
Entry term(s): 4F2 Antigen, Heavy Chain
4F2 Heavy Chain
4F2HC Subunit
Antigen 4F2, Heavy Chain
Antigens, CD98 Heavy Chain
CD98 Antigen Heavy Chain
CD98 Antigens Heavy Chain
FRP 1 Heavy Chain
FRP-1 Heavy Chain
SLC3A2 Protein
Solute Carrier Family 3 Member 2
Tree number(s): D12.776.157.530.200.374.750.500.250
D12.776.157.530.200.500.500.500.250
D12.776.157.530.937.313.500.250
D12.776.543.585.200.374.750.500.250
D12.776.543.585.200.500.500.500.250
D12.776.543.585.937.313.500.250
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D027282
Scope note: A transmembrane glycoprotein subunit that can dimerize with a variety of light chain subunits such as SLC7A5; SLC7A6, and 4F2 LIGHT CHAINS. This protein subunit serves a diverse array of functions including amino acid transport and cell fusion. Its function is altered depending which of the light chain subunits it interacts with.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Antigens, CD (1996-2001)
Carrier Proteins (1996-2001)
Public MeSH Note: 2018; see ANTIGENS, CD98 2002-2017; 4F2 ANTIGEN, HEAVY CHAIN was indexed under CARRIER PROTEINS and ANTIGENS, CD 1996-2001
History Note: 2018 (2002)
DeCS ID: 36159
Unique ID: D027282
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2002/01/01
Date of Entry: 2001/07/25
Revision Date: 2017/05/24
Fusion Regulatory Protein 1, Heavy Chain - Preferred
Concept UI M0379771
Scope note A transmembrane glycoprotein subunit that can dimerize with a variety of light chain subunits such as SLC7A5; SLC7A6, and 4F2 LIGHT CHAINS. This protein subunit serves a diverse array of functions including amino acid transport and cell fusion. Its function is altered depending which of the light chain subunits it interacts with.
Preferred term Fusion Regulatory Protein 1, Heavy Chain
Entry term(s) 4F2 Antigen, Heavy Chain
4F2 Heavy Chain
4F2HC Subunit
Antigen 4F2, Heavy Chain
Antigens, CD98 Heavy Chain
CD98 Antigen Heavy Chain
CD98 Antigens Heavy Chain
FRP 1 Heavy Chain
FRP-1 Heavy Chain
SLC3A2 Protein
Solute Carrier Family 3 Member 2



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