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Descriptor English: ADP-ribosyl Cyclase
Descriptor Spanish: ADP-Ribosil Ciclasa
Descriptor ADP-ribosil ciclasa
Entry term(s) ADP-ribosa ciclasa
Scope note: Enzima de membrana o citosólica que cataliza la síntesis del ADP-RIBOSA CÍCLICA (ADPRc) a partir de la nicotinamida adenina dinucleótido (NAD). Generalmente esta enzima cataliza la hidrólisis de la ADPRc para formar ADP-RIBOSA y en ocasiones la síntesis de ADP-ribosa cíclica 2' fosfato (ADPRc-2'-P) a partir del NADP.
Descriptor Portuguese: ADP-Ribosil Ciclase
Descriptor French: ADP-ribosyl cyclase
Entry term(s): 2' P ADPR Cyclase
2' Phospho adenosine Diphosphate Ribose Cyclase
2'-P-ADPR Cyclase
2'-Phospho-adenosine Diphosphate Ribose Cyclase
ADP Ribose Cyclase
ADP ribosyl Cyclase
ADP-ribose Hydrolase, Cyclic
ADPR Cyclase
Adenosine Diphosphate Ribose Cyclase
Cyclase, 2'-P-ADPR
Cyclase, ADP Ribose
Cyclase, ADP-ribosyl
Cyclase, ADPR
Cyclic ADP ribose Hydrolase
Cyclic ADP-ribose Hydrolase
Hydrolase, Cyclic ADP-ribose
Hydrolase, cADPR
Ribose Cyclase, ADP
cADPR Hydrolase
Tree number(s): D08.811.277.450.430.400.060
D08.811.913.400.725.115.660.060
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D036541
Scope note: A membrane-bound or cytosolic enzyme that catalyzes the synthesis of CYCLIC ADP-RIBOSE (cADPR) from nicotinamide adenine dinucleotide (NAD). This enzyme generally catalyzes the hydrolysis of cADPR to ADP-RIBOSE, as well, and sometimes the synthesis of cyclic ADP-ribose 2' phosphate (2'-P-cADPR) from NADP.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.2.2.5
Previous Indexing: Antigens, Differentiation (1991-2002)
NAD+ Nucleosidase (1993-2002)
Public MeSH Note: 2003; ADP-RIBOSYL CYCLASE was indexed under ANTIGENS, DIFFERENTIATION 1988-2002, NUCLEOSIDASES 1988-1997, and NAD+ NUCLEOSIDASES 1998-2002
History Note: 2003; use CD38 ANTIGEN (NM) 1988-2002
DeCS ID: 37324
Unique ID: D036541
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2003/01/01
Date of Entry: 2002/07/02
Revision Date: 2013/07/09
ADP-ribosyl Cyclase - Preferred
Concept UI M0160282
Scope note A membrane-bound or cytosolic enzyme that catalyzes the synthesis of CYCLIC ADP-RIBOSE (cADPR) from nicotinamide adenine dinucleotide (NAD). This enzyme generally catalyzes the hydrolysis of cADPR to ADP-RIBOSE, as well, and sometimes the synthesis of cyclic ADP-ribose 2' phosphate (2'-P-cADPR) from NADP.
Preferred term ADP-ribosyl Cyclase
Entry term(s) ADP Ribose Cyclase
ADP ribosyl Cyclase
ADPR Cyclase
Adenosine Diphosphate Ribose Cyclase
Cyclase, ADP Ribose
Cyclase, ADP-ribosyl
Cyclase, ADPR
Ribose Cyclase, ADP
Cyclic ADP-ribose Hydrolase - Narrower
Concept UI M0410130
Scope note EC 3.2.2.5
Preferred term Cyclic ADP-ribose Hydrolase
Entry term(s) ADP-ribose Hydrolase, Cyclic
Cyclic ADP ribose Hydrolase
Hydrolase, Cyclic ADP-ribose
Hydrolase, cADPR
cADPR Hydrolase
2'-P-ADPR Cyclase - Narrower
Concept UI M0259134
Preferred term 2'-P-ADPR Cyclase
Entry term(s) 2' P ADPR Cyclase
2' Phospho adenosine Diphosphate Ribose Cyclase
2'-Phospho-adenosine Diphosphate Ribose Cyclase
Cyclase, 2'-P-ADPR



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