| Descriptor English: | ADP Ribose Transferases | ||||||
| Descriptor Spanish: |
ADP Ribosa Transferasas
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| Descriptor Portuguese: | ADP Ribose Transferases | ||||||
| Descriptor French: | ADP ribose transferases | ||||||
| Entry term(s): |
ADP Ribose Transferase ADP Ribosyltransferase ADP-Ribosyltransferase ADP-Ribosyltransferase, NAD ADP-Ribosyltransferase, NAD+ ADP-Ribosyltransferase, NAD-Agmatine ADP-Ribosyltransferase, NAD-Arginine ADP-Ribosyltransferase, NADP-Arginine ADP-ribose Transferases, Mono ADPRT ADPRTs ADPribose Transferase, Mono ADPribose Transferases, Mono ART Transferase ART Transferases ARTase ARTases Mono ADP Ribosyltransferase Mono ADP ribose Transferases Mono ADP-ribose Transferases Mono ADPribose Transferase Mono ADPribose Transferases Mono(ADP-Ribose) Transferase Mono(ADP-Ribose) Transferases Mono(ADP-Ribosyl)transferase Mono(ADPribosyl)transferase Mono-ADP-Ribosyltransferase MonoADPribosyltransferase NAD ADP Ribosyltransferase NAD ADP-Ribosyltransferase NAD Agmatine ADP Ribosyltransferase NAD Arginine ADP Ribosyltransferase NAD(+)-L-arginine ADP-D-ribosyltransferase NAD(P)(+)-Arginine ADP-Ribosyltransferase NAD+ ADP Ribosyltransferase NAD+ ADP-Ribosyltransferase NAD-Agmatine ADP-Ribosyltransferase NAD-Arginine ADP-Ribosyltransferase NADP ADPRTase NADP Arginine ADP Ribosyltransferase NADP-ADPRTase NADP-Arginine ADP-Ribosyltransferase Ribose Transferase, ADP Ribose Transferases, ADP Transferase, ADP Ribose Transferase, ART Transferase, Mono ADPribose Transferases, ADP Ribose Transferases, ART Transferases, Mono ADP-ribose Transferases, Mono ADPribose |
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| Tree number(s): |
D08.811.913.400.725.115 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D036002 | ||||||
| Scope note: | Enzymes that transfer the ADP-RIBOSE group of NAD or NADP to proteins or other small molecules. Transfer of ADP-ribose to water (i.e., hydrolysis) is catalyzed by the NADASES. The mono(ADP-ribose)transferases transfer a single ADP-ribose. POLY(ADP-RIBOSE) POLYMERASES transfer multiple units of ADP-ribose to protein targets, building POLY ADENOSINE DIPHOSPHATE RIBOSE in linear or branched chains. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.4.2.- | ||||||
| Public MeSH Note: | 2003; see NAD(P)(+)-ARGININE ADP-RIBOSYLTRANSFERASE 1992-2002, see NAD-ARGININE ADP-RIBOSYLTRANSFERASE 1989-1991; for NAD+ ADP-RIBOSYLTRANSFERASE see NAD+ ADP-RIBOSYLTRANSFERASE 1992-2002, see POLY ADP RIBOSE POLYMERASE 1988-1991; for MONO-ADP-RIBOSYLTRANSFERASE and NAD-ARGININE ADP-RIBOSYLTRANSFERASE and NADP-ARGININE ADP-RIBOSYLTRANSFERASE see NAD(P)(+)-ARGININE ADP-RIBOSYLTRANSFERASE 1992-2002, see NAD-ARGININE ADP-RIBOSYLTRANSFERASE 1989-1991 |
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| History Note: | 2003; for NAD+ ADP-RIBOSYLTRANSFERASE use POLY(ADP-RIBOSE) POLYMERASES 1988-2002 |
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| Related: |
ADP-Ribosylation
MeSH | ||||||
| DeCS ID: | 30439 | ||||||
| Unique ID: | D036002 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2003/01/01 | ||||||
| Date of Entry: | 2002/07/02 | ||||||
| Revision Date: | 2017/04/14 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes
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ADP Ribose Transferases
- Preferred
Mono(ADP-Ribose) Transferases
- Narrower
NAD(P)(+)-Arginine ADP-Ribosyltransferase
- Narrower
NAD+ ADP-Ribosyltransferase
- Narrower
| Concept UI |
M0408809 |
| Scope note | Enzymes that transfer the ADP-RIBOSE group of NAD or NADP to proteins or other small molecules. Transfer of ADP-ribose to water (i.e., hydrolysis) is catalyzed by the NADASES. The mono(ADP-ribose)transferases transfer a single ADP-ribose. POLY(ADP-RIBOSE) POLYMERASES transfer multiple units of ADP-ribose to protein targets, building POLY ADENOSINE DIPHOSPHATE RIBOSE in linear or branched chains. |
| Preferred term | ADP Ribose Transferases |
| Entry term(s) |
ADP Ribose Transferase ADP Ribosyltransferase ADP-Ribosyltransferase ADPRT ADPRTs ART Transferase ART Transferases ARTase ARTases Ribose Transferase, ADP Ribose Transferases, ADP Transferase, ADP Ribose Transferase, ART Transferases, ADP Ribose Transferases, ART |
| Concept UI |
M0412050 |
| Scope note | Enzymes that catalyze the transfer of one ADP-ribose moiety from NAD+ to an amino acid residue in specific protein substrates. This reaction is catalyzed by prokaryotic and eukaryotic enzymes. Mono-ADP-ribosylation is a mechanism of action common to several bacterial toxins. |
| Preferred term | Mono(ADP-Ribose) Transferases |
| Entry term(s) |
ADP-ribose Transferases, Mono ADPribose Transferase, Mono ADPribose Transferases, Mono Mono ADP Ribosyltransferase Mono ADP ribose Transferases Mono ADP-ribose Transferases Mono ADPribose Transferase Mono ADPribose Transferases Mono(ADP-Ribose) Transferase Mono(ADP-Ribosyl)transferase Mono(ADPribosyl)transferase Mono-ADP-Ribosyltransferase MonoADPribosyltransferase Transferase, Mono ADPribose Transferases, Mono ADP-ribose Transferases, Mono ADPribose |
| Concept UI |
M0023658 |
| Scope note | An enzyme that catalyzes the transfer of the ADP-ribose moiety from NAD+ or NADP+ to specific protein substrates with arginine, arginine-type compounds, agmatine, or guanidine as acceptors. This mono-ADP-ribosylation reaction is the mechanism of action common to several bacterial toxins affecting profound changes in cellular metabolism, such as activation of adenylate cyclase, regulation of protein synthesis at the level of elongation factor 2, and ion transport across biological membranes. |
| Preferred term | NAD(P)(+)-Arginine ADP-Ribosyltransferase |
| Entry term(s) |
ADP-Ribosyltransferase, NAD-Agmatine ADP-Ribosyltransferase, NAD-Arginine ADP-Ribosyltransferase, NADP-Arginine NAD Agmatine ADP Ribosyltransferase NAD Arginine ADP Ribosyltransferase NAD(+)-L-arginine ADP-D-ribosyltransferase NAD-Agmatine ADP-Ribosyltransferase NAD-Arginine ADP-Ribosyltransferase NADP ADPRTase NADP Arginine ADP Ribosyltransferase NADP-ADPRTase NADP-Arginine ADP-Ribosyltransferase |
| Concept UI |
M0415110 |
| Scope note | An enzyme that catalyze the transfer of ADP-RIBOSE from NAD+ to an amino acid residue in a specific protein substrate. This reaction is catalyzed by both mono(ADP-ribose) transferases as well as POLY(ADP-RIBOSE) POLYMERASES. When the term NAD+ ADP-Ribosyltransferase refers to EC 2.4.2.30 it is referring to POLY(ADP-RIBOSE) POLYMERASES. |
| Preferred term | NAD+ ADP-Ribosyltransferase |
| Entry term(s) |
ADP-Ribosyltransferase, NAD ADP-Ribosyltransferase, NAD+ NAD ADP Ribosyltransferase NAD ADP-Ribosyltransferase NAD+ ADP Ribosyltransferase |
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