Descriptor English: | Eukaryotic Initiation Factor-4A | ||||||
Descriptor Spanish: |
Factor 4A Eucariótico de Iniciación
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Descriptor Portuguese: | Fator de Iniciação 4A em Eucariotos | ||||||
Descriptor French: | Facteur-4A d'initiation eucaryote | ||||||
Entry term(s): |
EIF-4A EIF-4A1 EIF-4A2 EIF-4A3 EIF4AIII Eukaryotic Initiation Factor 4A Eukaryotic Initiation Factor 4A1 Eukaryotic Initiation Factor 4A2 Eukaryotic Initiation Factor 4A3 Eukaryotic Initiation Factor EIF 4A Eukaryotic Initiation Factor EIF-4A Eukaryotic Initiation Factor-4A1 Eukaryotic Initiation Factor-4A2 Eukaryotic Initiation Factor-4A3 Eukaryotic Peptide Initiation Factor 4A Eukaryotic Peptide Initiation Factor-4A Eukaryotic Translation Initiation Factor 4AIII Eukaryotic Translation-Initiation Factor 4AIII Factor-4A1, Eukaryotic Initiation Factor-4A2, Eukaryotic Initiation Factor-4A3, Eukaryotic Initiation Initiation Factor-4A, Eukaryotic Initiation Factor-4A1, Eukaryotic Initiation Factor-4A2, Eukaryotic Initiation Factor-4A3, Eukaryotic Peptide Initiation Factor EIF 4A Peptide Initiation Factor EIF-4A |
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Tree number(s): |
D08.811.913.696.445.735.720.500 D12.776.835.725.868.500.500 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D039601 | ||||||
Scope note: | A component of eukaryotic initiation factor 4F that as an RNA helicase involved in unwinding the secondary structure of the 5' UNTRANSLATED REGION of MRNA. The unwinding facilitates the binding of the 40S ribosomal subunit. |
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Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Registry Number: | EC 2.7.7.- | ||||||
Previous Indexing: |
Peptide Initiation Factors (1980-2002) |
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Public MeSH Note: | 2003; EIF-4A (now EUKARYOTIC INITIATION FACTOR-4A) was indexed under PEPTIDE INITIATION FACTORS 1980-2002 |
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History Note: | 2003; use EUKARYOTIC INITIATION FACTOR-F4A (NM) 1980-2001 |
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DeCS ID: | 37337 | ||||||
Unique ID: | D039601 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 2003/01/01 | ||||||
Date of Entry: | 2002/07/03 | ||||||
Revision Date: | 2003/07/09 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Eukaryotic Initiation Factor-4A
- Preferred
Eukaryotic Initiation Factor-4A2
- Narrower
Eukaryotic Initiation Factor-4A3
- Narrower
Eukaryotic Initiation Factor-4A1
- Narrower
Concept UI |
M0086510 |
Scope note | A component of eukaryotic initiation factor 4F that as an RNA helicase involved in unwinding the secondary structure of the 5' UNTRANSLATED REGION of MRNA. The unwinding facilitates the binding of the 40S ribosomal subunit. |
Preferred term | Eukaryotic Initiation Factor-4A |
Entry term(s) |
EIF-4A Eukaryotic Initiation Factor 4A Eukaryotic Initiation Factor EIF 4A Eukaryotic Initiation Factor EIF-4A Eukaryotic Peptide Initiation Factor 4A Eukaryotic Peptide Initiation Factor-4A Initiation Factor-4A, Eukaryotic Peptide Initiation Factor EIF 4A Peptide Initiation Factor EIF-4A |
Concept UI |
M0086507 |
Preferred term | Eukaryotic Initiation Factor-4A2 |
Entry term(s) |
EIF-4A2 Eukaryotic Initiation Factor 4A2 Factor-4A2, Eukaryotic Initiation Initiation Factor-4A2, Eukaryotic |
Concept UI |
M0350427 |
Preferred term | Eukaryotic Initiation Factor-4A3 |
Entry term(s) |
EIF-4A3 EIF4AIII Eukaryotic Initiation Factor 4A3 Eukaryotic Translation Initiation Factor 4AIII Eukaryotic Translation-Initiation Factor 4AIII Factor-4A3, Eukaryotic Initiation Initiation Factor-4A3, Eukaryotic |
Concept UI |
M0086506 |
Preferred term | Eukaryotic Initiation Factor-4A1 |
Entry term(s) |
EIF-4A1 Eukaryotic Initiation Factor 4A1 Factor-4A1, Eukaryotic Initiation Initiation Factor-4A1, Eukaryotic |
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