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Descriptor English: Pulmonary Surfactant-Associated Protein A
Descriptor Spanish: Proteína A Asociada a Surfactante Pulmonar
Descriptor proteína A asociada a surfactante pulmonar
Scope note: Proteína abundante asocida a surfactante pulmonar que se une a diiversos patógenos pulmonares para su opsonización. Asimismo, estimula los MACRÓFAGOS para efectuar la FAGOCITOSIS de microorganismos. La proteína A de surfactante contiene un dominio tipo colágeno N-terminal y un dominio lectina C-terminal que son caracteristicos de los miembros de la familia de proteínas de la colectina.
Descriptor Portuguese: Proteína A Associada a Surfactante Pulmonar
Descriptor French: Protéine A associée au surfactant pulmonaire
Entry term(s): Pulmonary Surfactant Associated Protein A
SP A Protein
SP-A Protein
Surfactant Protein A
Tree number(s): D12.776.503.280.249.600
D12.776.823.100
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D037662
Scope note: An abundant pulmonary surfactant-associated protein that binds to a variety of lung pathogens, resulting in their opsinization. It also stimulates MACROPHAGES to undergo PHAGOCYTOSIS of microorganisms. Surfactant protein A contains a N-terminal collagen-like domain and a C-terminal lectin domain that are characteristic of members of the collectin family of proteins.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Pulmonary Surfactants
Previous Indexing: Proteolipids (1991-2002)
Pulmonary Surfactants (1991-2002)
Public MeSH Note: 2003; SURFACTANT PROTEIN A & SP-A PROTEIN was indexed under PROTEOLIPIDS & PULMONARY SURFACTANTS 1991-2002
History Note: 2003; for SURFACTANT PROTEIN A & SP-A PROTEIN use PULMONARY SURFACTANT-ASSOCIATED PROTEINS (NM) 1991-2002
Entry Version: PULMONARY SURFACTANT ASSOC PROTEIN A
DeCS ID: 37462
Unique ID: D037662
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 2005/06/30
Pulmonary Surfactant-Associated Protein A - Preferred
Concept UI M0097367
Scope note An abundant pulmonary surfactant-associated protein that binds to a variety of lung pathogens, resulting in their opsinization. It also stimulates MACROPHAGES to undergo PHAGOCYTOSIS of microorganisms. Surfactant protein A contains a N-terminal collagen-like domain and a C-terminal lectin domain that are characteristic of members of the collectin family of proteins.
Preferred term Pulmonary Surfactant-Associated Protein A
Entry term(s) Pulmonary Surfactant Associated Protein A
SP A Protein
SP-A Protein
Surfactant Protein A



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