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Descriptor English: Thymine DNA Glycosylase
Descriptor Spanish: Timina ADN Glicosilasa
Descriptor timina ADN glicosilasa
Entry term(s) timina-ADN-glucosilasa
Scope note: Enzima que elimina las bases TIMINA y URACILO con errores de apareamiento con la GUANINA mediante la hidrólisis de su enlace N-glicosídico. Estos nucleótidos con errores de apareamiento se producen generalmente por la DESAMINACIÓN hidrolítica de la 5-METILCITOSINA que da lugar a la timina.
Descriptor Portuguese: Timina DNA Glicosilase
Descriptor French: Thymine DNA glycosylase
Entry term(s): DNA Glycosylase, Thymine
G T Mismatch Specific Thymine DNA Glycosylase
G-T Mismatch-Specific Thymine DNA Glycosylase
Glycol Glycosylase, Thymine
Glycosylase, Thymine DNA
Glycosylase, Thymine Glycol
Thymine Glycol DNA Glycosylase
Thymine Glycol Glycosylase
Tree number(s): D08.811.074.249.750
D08.811.277.450.430.099.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D044502
Scope note: An enzyme that removes THYMINE and URACIL bases mispaired with GUANINE through hydrolysis of their N-glycosidic bond. These mispaired nucleotides generally occur through the hydrolytic DEAMINATION of 5-METHYLCYTOSINE to thymine.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.2.2.-
Previous Indexing: Endodeoxyribonucleases (1991-2003)
Public MeSH Note: 2004; THYMIDINE DNA GLYCOSYLASE was indexed under ENDODEOXYRIBONUCLEASES 1991-2003
History Note: 2004; use THYMINE DNA GLYCOSYLASE (NM) 1991-2003
DeCS ID: 38128
Unique ID: D044502
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2006/07/05
Thymine DNA Glycosylase - Preferred
Concept UI M0073437
Scope note An enzyme that removes THYMINE and URACIL bases mispaired with GUANINE through hydrolysis of their N-glycosidic bond. These mispaired nucleotides generally occur through the hydrolytic DEAMINATION of 5-METHYLCYTOSINE to thymine.
Preferred term Thymine DNA Glycosylase
Entry term(s) DNA Glycosylase, Thymine
G T Mismatch Specific Thymine DNA Glycosylase
G-T Mismatch-Specific Thymine DNA Glycosylase
Glycol Glycosylase, Thymine
Glycosylase, Thymine DNA
Glycosylase, Thymine Glycol
Thymine Glycol DNA Glycosylase
Thymine Glycol Glycosylase



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