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Descriptor English: 5,10-Methylenetetrahydrofolate Reductase (FADH2)
Descriptor Spanish: 5,10-Metilenotetrahidrofolato Reductasa (FADH2)
Descriptor Portuguese: 5,10-Metilenotetra-Hidrofolato Redutase (FADH2)
Descriptor French: 5,10-Methylenetetrahydrofolate reductase (FADH2)
Entry term(s): 5,10-Methylenetetrahydrofolate Reductase (FADH)
Tree number(s): D08.811.682.550
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D045103
Scope note: An FAD-dependent oxidoreductase found primarily in BACTERIA. It is specific for the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate. This enzyme was formerly listed as EC 1.1.1.68 and 1.1.99.15.
Annotation:
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 1.5.1.20
Previous Indexing: Alcohol Oxidoreductases (1974-2003)
Folic Acid (1970-1973)
Oxidoreductases (1974-1986)
Tetrahydrofolates (1974-1982)
Public MeSH Note: 2004; 5,10-METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2) was indexed under OXIDOREDUCTASES 1987-2003, under ALCOHOL OXIDOREDUCTASES 1974-1986, under TETRAHYDROFOLATES 1974-1982 & under FOLIC ACIDS 1970-1973
History Note: 2004; use 5,10-METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2) (NM) 1980-2003
DeCS ID: 38196
Unique ID: D045103
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2013/07/09
5,10-Methylenetetrahydrofolate Reductase (FADH2) - Preferred
Concept UI M0076715
Scope note An FAD-dependent oxidoreductase found primarily in BACTERIA. It is specific for the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate. This enzyme was formerly listed as EC 1.1.1.68 and 1.1.99.15.
Preferred term 5,10-Methylenetetrahydrofolate Reductase (FADH2)
Entry term(s) 5,10-Methylenetetrahydrofolate Reductase (FADH)



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