| Descriptor English: | Receptor, PAR-2 | ||||||
| Descriptor Spanish: |
Receptor PAR-2
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| Descriptor Portuguese: | Receptor PAR-2 | ||||||
| Descriptor French: | Récepteur de type PAR-2 | ||||||
| Entry term(s): |
PAR 2 Receptor PAR-2 Receptor PAR2 Receptor Protease Activated Receptor 2 Protease-Activated Receptor 2 Proteinase Activated Receptor 2 Receptor 2, Protease-Activated Receptor, PAR 2 Receptor, PAR2 Receptor, Trypsin Receptors, Trypsin Trypsin Receptor Trypsin Receptors |
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| Tree number(s): |
D12.776.543.750.695.035 D12.776.543.750.792.249 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D044464 | ||||||
| Scope note: | A G-protein-coupled, proteinase-activated receptor that is expressed in a variety of tissues including ENDOTHELIUM; LEUKOCYTES; and the GASTROINTESTINAL TRACT. The receptor is activated by TRYPSIN, which cleaves off the N-terminal peptide from the receptor. The new N-terminal peptide is a cryptic ligand for the receptor. The uncleaved receptor can also be activated by the N-terminal peptide present on the activated THROMBIN RECEPTOR and by small synthetic peptides that contain the unmasked N-terminal sequence. |
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| Allowable Qualifiers: |
AD administration & dosage AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CH chemistry CL classification DE drug effects DF deficiency GE genetics HI history IM immunology IP isolation & purification ME metabolism PH physiology RE radiation effects TU therapeutic use UL ultrastructure |
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| Previous Indexing: |
Receptors, Thrombin (1994-2003) |
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| Public MeSH Note: | 2004; PROTEINASE ACTIVATED RECEPTOR 2 (now RECEPTOR, PAR-2) was indexed under RECEPTORS, THROMBIN 1994-2003; TRYPSIN RECEPTOR (now RECEPTOR, PAR-2) was indexed under RECEPTORS, CELL SURFACE 1986-2003 |
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| History Note: | 2004; use RECEPTOR, PAR-2 (NM) 1994-2003; for TRYPSIN RECEPTOR use RECEPTOR, PAR-2 (NM) 1986-2003 |
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| Entry Version: | RECEPT PAR 2 |
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| DeCS ID: | 38263 | ||||||
| Unique ID: | D044464 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2004/01/01 | ||||||
| Date of Entry: | 2003/07/09 | ||||||
| Revision Date: | 2016/06/17 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Receptor, PAR-2
- Preferred
| Concept UI |
M0236839 |
| Scope note | A G-protein-coupled, proteinase-activated receptor that is expressed in a variety of tissues including ENDOTHELIUM; LEUKOCYTES; and the GASTROINTESTINAL TRACT. The receptor is activated by TRYPSIN, which cleaves off the N-terminal peptide from the receptor. The new N-terminal peptide is a cryptic ligand for the receptor. The uncleaved receptor can also be activated by the N-terminal peptide present on the activated THROMBIN RECEPTOR and by small synthetic peptides that contain the unmasked N-terminal sequence. |
| Preferred term | Receptor, PAR-2 |
| Entry term(s) |
PAR 2 Receptor PAR-2 Receptor PAR2 Receptor Protease Activated Receptor 2 Protease-Activated Receptor 2 Proteinase Activated Receptor 2 Receptor 2, Protease-Activated Receptor, PAR 2 Receptor, PAR2 Receptor, Trypsin Receptors, Trypsin Trypsin Receptor Trypsin Receptors |
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