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Descriptor English: DNA Sequence, Unstable
Descriptor Spanish: Secuencia de ADN Inestable
Descriptor secuencia de ADN inestable
Entry term(s) secuencia inestable de ADN
Scope note: Región de ADN que es muy polimorfa y tiene tendencia a presentar rupturas, reordenamiento de cadenas y otras MUTACIONES debido a la naturaleza de su secuencia. Con frecuencia estas zonas contienen secuencias palindrómicas o repetitivas (SECUENCIAS REPETITIVAS DEL ÁCIDO NUCLEICO). La variabilidad de la estabilidad de la secuencia del ADN se observa en los SITIOS FRÁGILES DE LOS CROMOSOMAS.
Descriptor Portuguese: Sequência de DNA Instável
Descriptor French: Séquence instable d'ADN
Entry term(s): DNA Sequences, Unstable
Sequence, Unstable DNA
Sequences, Unstable DNA
Unstable DNA Sequence
Unstable DNA Sequences
Tree number(s): G05.360.340.024.189
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D043243
Scope note: A region of DNA that is highly polymorphic and is prone to strand breaks, rearrangements or other MUTATIONS because of the nature of its sequence. These regions often harbor palindromic, or repetitive sequences (REPETITIVE SEQUENCES, NUCLEIC ACID). Variability in stability of the DNA sequence is seen at CHROMOSOME FRAGILE SITES.
Allowable Qualifiers: DE drug effects
ES ethics
GE genetics
IM immunology
PH physiology
RE radiation effects
Public MeSH Note: 2004(1998); see TRINUCLEOTIDE REPEAT EXPANSION 1999-2003
History Note: 2004 (1998); use TRINUCLEOTIDE REPEAT EXPANSION 1998-2003
Entry Version: DNA SEQ UNSTABLE
Related: Chromosome Fragility MeSH
Genomic Instability MeSH
DeCS ID: 38394
Unique ID: D043243
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2008/07/08
DNA Sequence, Unstable - Preferred
Concept UI M0029212
Scope note A region of DNA that is highly polymorphic and is prone to strand breaks, rearrangements or other MUTATIONS because of the nature of its sequence. These regions often harbor palindromic, or repetitive sequences (REPETITIVE SEQUENCES, NUCLEIC ACID). Variability in stability of the DNA sequence is seen at CHROMOSOME FRAGILE SITES.
Preferred term DNA Sequence, Unstable
Entry term(s) DNA Sequences, Unstable
Sequence, Unstable DNA
Sequences, Unstable DNA
Unstable DNA Sequence
Unstable DNA Sequences



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