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Descriptor in English: DNA Sequence, Unstable
Descriptor in Spanish: Secuencia de ADN Inestable
Descriptor in Portuguese: Sequência de DNA Instável
Descriptor in French: Séquence instable d'ADN
Entry term(s): DNA Sequences, Unstable
Sequence, Unstable DNA
Sequences, Unstable DNA
Unstable DNA Sequence
Unstable DNA Sequences
Tree number(s): G05.360.340.024.189
Scope note: A region of DNA that is highly polymorphic and is prone to strand breaks, rearrangements or other MUTATIONS because of the nature of its sequence. These regions often harbor palindromic, or repetitive sequences (REPETITIVE SEQUENCES, NUCLEIC ACID). Variability in stability of the DNA sequence is seen at CHROMOSOME FRAGILE SITES.
Allowable Qualifiers: DE drug effects
ES ethics
GE genetics
IM immunology
PH physiology
RE radiation effects
History Note: 2004 (1998); use TRINUCLEOTIDE REPEAT EXPANSION 1998-2003
See also the descriptors: Chromosome Fragility MeSH
Genomic Instability MeSH
DeCS UI: 38394
Descriptor UI: D043243
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2008/07/08
DNA Sequence, Unstable - Preferred
Concept UI M0029212
Scope note A region of DNA that is highly polymorphic and is prone to strand breaks, rearrangements or other MUTATIONS because of the nature of its sequence. These regions often harbor palindromic, or repetitive sequences (REPETITIVE SEQUENCES, NUCLEIC ACID). Variability in stability of the DNA sequence is seen at CHROMOSOME FRAGILE SITES.
Preferred term DNA Sequence, Unstable
Entry term(s) DNA Sequences, Unstable
Sequence, Unstable DNA
Sequences, Unstable DNA
Unstable DNA Sequence
Unstable DNA Sequences



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