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Descriptor English: CADASIL
Descriptor Spanish: CADASIL
Descriptor cadasil
Entry term(s) demencia vascular hereditaria
Scope note: Arteriopatía cerebral familiar relacionada con el cromosoma 19q12 y caracterizada por la presencia de depósitos granulares en las ARTERIAS CEREBRALES de pequeño calibre, que da lugar a ICTUS isquémico, PARÁLISIS PSEUDOBULBAR e infartos subcorticales múltiples (INFARTO CEREBRAL). El término CADASIL es el acrónimo de arteriopatía cerebral autosómica dominante con infartos subcorticales y leucoencefalopatía (Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy). La arteriopatía de tipo CADASIL difiere de la ENFERMEDAD DE BINSWANGER por la presencia de MIGRAÑA CON AURA y generalmente por la ausencia de antecedentes de hipertensión arterial. (Bradley et al, Neurology in Clinical Practice, 2000, p1146).Arteriopatía cerebral familiar relacionada con el cromosoma 19q12 y caracterizada por la presencia de depósitos granulares en las ARTERIAS CEREBRALES de pequeño calibre, que da lugar a ICTUS isquémico, PARÁLISIS PSEUDOBULBAR e infartos subcorticales múltiples (INFARTO DE HEMISFERIO CEREBRAL). El términi CADASIL es un acrónimo de arteriopatía cerebral autosómica dominante con infartos subcorticales y leucoencefalopatía (en inglés: Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy). La arteriopatía de tipo CADASIL difiere de la ENFERMEDAD DE BINSWANGER por la presencia de MIGRAÑA CON AURA y generalmente por la ausencia de antecentes de HIPERTENSIÓN arterial. (Bradley et al, Neurology in Clinical Practice, 2000, p1146)
Descriptor Portuguese: CADASIL
Descriptor French: CADASIL
Entry term(s): CADASILM
Cerebral Arteriopathy with Subcortical Infarcts and Leukoencephalopathy
Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy
Dementia, Hereditary Multi Infarct Type
Dementia, Hereditary Multi-Infarct Type
Tree number(s): C10.228.140.300.150.477.200.100
C10.228.140.300.275.249
C10.228.140.300.400.203
C10.228.140.300.510.200.175
C10.228.140.300.775.200.200.100
C10.228.140.380.230.124
C14.907.253.092.477.200.100
C14.907.253.329.249
C14.907.253.560.200.175
C14.907.253.855.200.200.100
C16.320.129
C23.550.513.355.250.200.100
C23.550.717.489.250.200.100
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D046589
Scope note: A familial, cerebral arteriopathy mapped to chromosome 19q12, and characterized by the presence of granular deposits in small CEREBRAL ARTERIES producing ischemic STROKE; PSEUDOBULBAR PALSY; and multiple subcortical infarcts (CEREBRAL INFARCTION). CADASIL is an acronym for Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy. CADASIL differs from BINSWANGER DISEASE by the presence of MIGRAINE WITH AURA and usually by the lack of history of arterial HYPERTENSION. (From Bradley et al, Neurology in Clinical Practice, 2000, p1146)
Allowable Qualifiers: BL blood
CF cerebrospinal fluid
CI chemically induced
CL classification
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SU surgery
TH therapy
UR urine
VE veterinary
VI virology
Previous Indexing: Cerebrovascular Disorders (1994-2004)
Dementia, Multi-Infarct (1994-2004)
Public MeSH Note: 2005; see DEMENTIA, MULTI-INFARCT 2000-2004
History Note: 2005; use DEMENTIA, MULTI-INFARCT 2000-2004
DeCS ID: 38632
Unique ID: D046589
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2005/01/01
Date of Entry: 2004/07/07
Revision Date: 2013/07/08
CADASIL - Preferred
Concept UI M0334725
Scope note A familial, cerebral arteriopathy mapped to chromosome 19q12, and characterized by the presence of granular deposits in small CEREBRAL ARTERIES producing ischemic STROKE; PSEUDOBULBAR PALSY; and multiple subcortical infarcts (CEREBRAL INFARCTION). CADASIL is an acronym for Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy. CADASIL differs from BINSWANGER DISEASE by the presence of MIGRAINE WITH AURA and usually by the lack of history of arterial HYPERTENSION. (From Bradley et al, Neurology in Clinical Practice, 2000, p1146)
Preferred term CADASIL
Entry term(s) Cerebral Arteriopathy with Subcortical Infarcts and Leukoencephalopathy
Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy
Dementia, Hereditary Multi Infarct Type
Dementia, Hereditary Multi-Infarct Type
CADASILM - Related but not broader or narrower
Concept UI M0454809
Scope note A subvariety of CADASIL characterized by the high frequency of MIGRAINE. The acronym stands for Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts, Leukoencephalopathy, and Migraine.
Preferred term CADASILM



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