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Descriptor in English: Sphingolipid Activator Proteins
Descriptor in Spanish: Proteínas Activadoras de Esfingolípidos
Descriptor in Portuguese: Proteínas Ativadoras de Esfingolipídeos
Descriptor in French: Protéines activatrices des sphingolipides
Entry term(s): Cerebroside Sulfate Activator Protein
G(M1) Activator Protein
G(M1) Ganglioside Activating Factor
GM1 Activator Protein
Ganglioside Degradation Activator Protein
Ganglioside Hydrolysis Activator Proteins
Hexosaminidase A Activating Protein
Hexosaminidase Activating Factor
Tree number(s): D08.211.790
Scope note: A family of glycoprotein cofactors that are required for the efficient catabolization of SPHINGOLIPIDS by specific acid hydrolases such as GLUCOSYLCERAMIDASE; GALACTOCEREBROSIDASE; BETA-N-ACETYLHEXOSAMINIDASE; and CEREBROSIDE-SULFATASE.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
History Note: 2005(1977)
DeCS UI: 38689
Descriptor UI: D049128
Date Established: 2005/01/01
Date of Entry: 2004/07/07
Revision Date: 2006/07/05
Sphingolipid Activator Proteins - Preferred
Concept UI M0463628
Scope note A family of glycoprotein cofactors that are required for the efficient catabolization of SPHINGOLIPIDS by specific acid hydrolases such as GLUCOSYLCERAMIDASE; GALACTOCEREBROSIDASE; BETA-N-ACETYLHEXOSAMINIDASE; and CEREBROSIDE-SULFATASE.
Preferred term Sphingolipid Activator Proteins
G(M1) Ganglioside Activating Factor - Narrower
Concept UI M0063211
Preferred term G(M1) Ganglioside Activating Factor
Entry term(s) G(M1) Activator Protein
GM1 Activator Protein
Hexosaminidase A Activating Protein - Narrower
Concept UI M0063219
Preferred term Hexosaminidase A Activating Protein
Entry term(s) Hexosaminidase Activating Factor
Cerebroside Sulfate Activator Protein - Related but not broader or narrower
Concept UI M0063217
Preferred term Cerebroside Sulfate Activator Protein
Ganglioside Hydrolysis Activator Proteins - Related but not broader or narrower
Concept UI M0063225
Preferred term Ganglioside Hydrolysis Activator Proteins
Entry term(s) Ganglioside Degradation Activator Protein



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