Search
Descriptor English: G(M2) Activator Protein
Descriptor Spanish: Proteína Activadora de G (M2)
Descriptor proteína activadora de G(M2)
Entry term(s) G(M2)AP
Scope note: Cofactor esencial para la degradación del GANGLIÓSIDO G(M2) por las BETA-N-ACETILHEXOSAMINIDASAS lisosómicas. Las mutaciones genéticas que dan lugar a la deficiencia de proteína activadora de G(M2) son una de las causas de la VARIANTE AB DE LA ENFERMEDAD DE TAY-SACHS.
Descriptor Portuguese: Proteína Ativadora de G(M2)
Descriptor French: Activateur protéique GM2
Entry term(s): Activator Protein, GM2
GM(2) Activating Protein
GM2 Activator Protein
Hexosaminidase Activator
Tree number(s): D08.211.790.249
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D049289
Scope note: An essential cofactor for the degradation of G(M2)GANGLIOSIDE by lysosomal BETA-N-ACETYLHEXOSAMINIDASES. Genetic mutations resulting in loss of G(M2) activator protein are one of the causes of TAY-SACHS DISEASE, AB VARIANT.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Proteins (1983-2004)
Public MeSH Note: 2005; G(M2) ACTIVATOR PROTEIN was indexed under PROTEINS 1983-2004
History Note: 2005(1983)
DeCS ID: 38690
Unique ID: D049289
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2005/01/01
Date of Entry: 2004/07/08
Revision Date: 2007/07/11
G(M2) Activator Protein - Preferred
Concept UI M0111676
Scope note An essential cofactor for the degradation of G(M2)GANGLIOSIDE by lysosomal BETA-N-ACETYLHEXOSAMINIDASES. Genetic mutations resulting in loss of G(M2) activator protein are one of the causes of TAY-SACHS DISEASE, AB VARIANT.
Preferred term G(M2) Activator Protein
Entry term(s) Activator Protein, GM2
GM(2) Activating Protein
GM2 Activator Protein
Hexosaminidase Activator



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey