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Descriptor English: Casein Kinase Ialpha
Descriptor Spanish: Caseína Quinasa Ialfa
Descriptor caseína cinasa I alfa
Entry term(s) caseína quinasa I alfa
Scope note: Isoenzima de la caseína cinasa I que interviene en las vías de señalización intracelular, incluyendo la VÍA DE SEÑALIZACIÓN WNT, el CICLO CELULAR, el transporte a través de membranas y el procesamiento del ARN. Existen múltiples isoformas de la caseína cinasa I alfa, debidas al CORTE Y EMPALME ALTERNATIVO.
Descriptor Portuguese: Caseína Quinase Ialfa
Descriptor French: Casein Kinase Ialpha
Entry term(s): Casein Kinase I alpha
Casein Kinase IalphaL
Casein Kinase IalphaLS
Casein Kinase IalphaS
Tree number(s): D05.500.117.750.100
D08.811.913.696.620.682.700.140.300.100
D12.776.476.563.140.300.100
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D048128
Scope note: A casein kinase I isoenzyme that plays a role in intracellular signaling pathways including the WNT SIGNALING PATHWAY, the CELL CYCLE, membrane trafficking, and RNA processing. Multiple isoforms of casein kinase I alpha exist and are due to ALTERNATIVE SPLICING.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.7.11.1
Previous Indexing: Protein Kinases (2000-2004)
Public MeSH Note: 2005; CASEIN KINASE IALPHA was indexed under PROTEIN KINASES 2000-2004
History Note: 2005(2000)
DeCS ID: 38709
Unique ID: D048128
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2005/01/01
Date of Entry: 2004/07/07
Revision Date: 2011/06/24
Casein Kinase Ialpha - Preferred
Concept UI M0072784
Scope note A casein kinase I isoenzyme that plays a role in intracellular signaling pathways including the WNT SIGNALING PATHWAY, the CELL CYCLE, membrane trafficking, and RNA processing. Multiple isoforms of casein kinase I alpha exist and are due to ALTERNATIVE SPLICING.
Preferred term Casein Kinase Ialpha
Entry term(s) Casein Kinase I alpha
Casein Kinase IalphaS - Narrower
Concept UI M0072787
Preferred term Casein Kinase IalphaS
Casein Kinase IalphaLS - Narrower
Concept UI M0072786
Preferred term Casein Kinase IalphaLS
Casein Kinase IalphaL - Narrower
Concept UI M0072785
Preferred term Casein Kinase IalphaL



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