| Descriptor English: | Mitogen-Activated Protein Kinase 8 | ||||||
| Descriptor Spanish: |
Proteína Quinasa 8 Activada por Mitógenos
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| Descriptor Portuguese: | Proteína Quinase 8 Ativada por Mitógeno | ||||||
| Descriptor French: | Mitogen-Activated Protein Kinase 8 | ||||||
| Entry term(s): |
JNK1 Kinase MAPK8 Mitogen Activated Protein Kinase MAPK8 Mitogen-Activated Protein Kinase Mitogen Activated Protein Kinase 8 SAP Kinase 1 SAP Kinase-1 SAPK1 Mitogen Activated Protein Kinase SAPK1 Mitogen-Activated Protein Kinase Stress Activated Protein Kinase 1 Stress Activated Protein Kinase JNK1 Stress Activated Protein Kinase gamma Stress-Activated Protein Kinase 1 Stress-Activated Protein Kinase JNK1 Stress-Activated Protein Kinase gamma c jun Kinase 1 c jun N Terminal Kinase 1 c-jun Kinase-1 c-jun N-Terminal Kinase 1 |
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| Tree number(s): |
D08.811.913.696.620.682.700.567.374.500 D12.776.476.563.567.374.500 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D048055 | ||||||
| Scope note: | A c-jun amino-terminal kinase that is activated by environmental stress and pro-inflammatory cytokines. Several isoforms of the protein with molecular sizes of 43 and 48 KD exist due to multiple ALTERNATIVE SPLICING. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 2.7.11.24 | ||||||
| Previous Indexing: |
Mitogen-Activated Protein Kinases (2000-2004) |
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| Public MeSH Note: | 2005; MITOGEN-ACTIVATED PROTEIN KINASE 8 was indexed under MITOGEN-ACTIVATED PROTEIN KINASES 2000-2004 |
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| History Note: | 2005(2000) |
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| DeCS ID: | 38732 | ||||||
| Unique ID: | D048055 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2005/01/01 | ||||||
| Date of Entry: | 2004/07/07 | ||||||
| Revision Date: | 2015/11/24 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Mitogen-Activated Protein Kinase 8
- Preferred
| Concept UI |
M0362611 |
| Scope note | A c-jun amino-terminal kinase that is activated by environmental stress and pro-inflammatory cytokines. Several isoforms of the protein with molecular sizes of 43 and 48 KD exist due to multiple ALTERNATIVE SPLICING. |
| Preferred term | Mitogen-Activated Protein Kinase 8 |
| Entry term(s) |
JNK1 Kinase MAPK8 Mitogen Activated Protein Kinase MAPK8 Mitogen-Activated Protein Kinase Mitogen Activated Protein Kinase 8 SAP Kinase 1 SAP Kinase-1 SAPK1 Mitogen Activated Protein Kinase SAPK1 Mitogen-Activated Protein Kinase Stress Activated Protein Kinase 1 Stress Activated Protein Kinase JNK1 Stress Activated Protein Kinase gamma Stress-Activated Protein Kinase 1 Stress-Activated Protein Kinase JNK1 Stress-Activated Protein Kinase gamma c jun Kinase 1 c jun N Terminal Kinase 1 c-jun Kinase-1 c-jun N-Terminal Kinase 1 |
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