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Descriptor English: Depressive Disorder, Major
Descriptor Spanish: Trastorno Depresivo Mayor
Descriptor trastorno depresivo mayor
Entry term(s) depresión involutiva
melancolía involutiva
parafrenia involutiva
psicosis involutiva
trastorno de depresión mayor
Scope note: Trastorno en el que cinco (o más) de los síntomas siguientes han estado presentes durante el mismo período de dos semanas y representan un cambio del funcionamiento previo; al menos uno de los síntomas es (1) estado de ánimo deprimido o (2) pérdida de interés o de placer. Los síntomas son: estado de ánimo deprimido la mayor parte del día, casi todos los días; disminución importante del interés o el placer por todas o casi todas las actividades la mayor parte del día, casi todos los días; pérdida importante de peso sin hacer dieta o aumento de peso; insomnio o hipersomnia casi todos los días; agitación o retraso psicomotor casi todos los días; fatiga o pérdida de energía casi todos los días; sentimiento de inutilidad o culpabilidad excesiva o inapropiada; disminución de la capacidad para pensar o concentrarse, o para tomar decisiones, casi todos los días; o pensamientos de muerte recurrentes, ideas suicidas recurrentes sin un plan determinado o intento de suicidio. (DSM-5)
Descriptor Portuguese: Transtorno Depressivo Maior
Descriptor French: Trouble dépressif majeur
Entry term(s): Depression, Involutional
Depressive Disorders, Major
Involutional Depression
Involutional Melancholia
Involutional Paraphrenia
Involutional Paraphrenias
Involutional Psychoses
Involutional Psychosis
Major Depressive Disorder
Major Depressive Disorders
Melancholia, Involutional
Paraphrenia, Involutional
Paraphrenias, Involutional
Psychoses, Involutional
Psychosis, Involutional
Tree number(s): F03.600.300.375
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D003865
Scope note: Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)
Allowable Qualifiers: BL blood
CF cerebrospinal fluid
CI chemically induced
CL classification
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
SU surgery
TH therapy
UR urine
VI virology
Public MeSH Note: 81; was PSYCHOSES, INVOLUTIONAL 1963-80
Online Note: use DEPRESSION, INVOLUTIONAL to search PSYCHOSES, INVOLUTIONAL & MELANCHOLIA, INVOLUTIONAL 1966-80
History Note: 81; was PSYCHOSES, INVOLUTIONAL 1963-80; MELANCHOLIA, INVOLUTIONAL was see under PSYCHOSES, INVOLUTIONAL 1963-78
Entry Version: DEPRESSIVE DIS MAJOR
DeCS ID: 3885
Unique ID: D003865
NLM Classification: WM 171.5
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1981/01/01
Date of Entry: 1999/01/01
Revision Date: 2019/03/22
Depressive Disorder, Major - Preferred
Concept UI M0006031
Scope note Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)
Preferred term Depressive Disorder, Major
Entry term(s) Depressive Disorders, Major
Major Depressive Disorder
Major Depressive Disorders
Psychosis, Involutional - Related but not broader or narrower
Concept UI M0522397
Scope note Severe mental disorder with onset in MIDDLE AGE, marked by withdrawal, abnormal affect, disturbed intellectual processes, and there may be regression.
Preferred term Psychosis, Involutional
Entry term(s) Involutional Psychoses
Involutional Psychosis
Psychoses, Involutional
Paraphrenia, Involutional - Narrower
Concept UI M0536747
Preferred term Paraphrenia, Involutional
Entry term(s) Involutional Paraphrenia
Involutional Paraphrenias
Paraphrenias, Involutional
Depression, Involutional - Related but not broader or narrower
Concept UI M0522396
Scope note Form of depression in those MIDDLE AGE with feelings of ANXIETY.
Preferred term Depression, Involutional
Entry term(s) Involutional Depression
Involutional Melancholia
Melancholia, Involutional



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