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Descriptor English: Inteins
Descriptor Spanish: Inteínas
Descriptor inteínas
Entry term(s) intrones proteicos
Scope note: Fragmentos internos de proteínas precursoras ( del inglés “INternal proTEINS”) que se eliminan de forma autocatalítica mediante el fenómeno de EMPALME DE PROTEÍNAS. Los fragmentos adyacentes (EXTEÍNAS) se unen para formar proteínas maduras. Se considera que las secuencias nucleotídicas que codifican las inteínas son ELEMENTOS GENÉTICOS MÓVILES. Las inteínas están constituidas por dominios procedentes del autoempalme y por un dominio con actividad endonucleasa que contribuye a la dispersión de las secuencias de la inteína por el genoma. Las mini-inteínas están constituidas sólo por dominios procedentes del autoempalme.
Descriptor Portuguese: Inteínas
Descriptor French: Intéines
Entry term(s): Intein
Intervening Protein Sequence
Intervening Protein Sequences
Intron, Protein
Introns, Protein
Protein Intron
Protein Introns
Protein Sequence, Intervening
Protein Sequences, Intervening
Sequence, Intervening Protein
Sequences, Intervening Protein
Tree number(s): G02.111.570.060.440
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D047668
Scope note: The internal fragments of precursor proteins (INternal proTEINS) that are autocatalytically removed by PROTEIN SPLICING. The flanking fragments (EXTEINS) are ligated forming mature proteins. The nucleic acid sequences coding for inteins are considered to be MOBILE GENETIC ELEMENTS. Inteins are composed of self-splicing domains and an endonuclease domain which plays a role in the spread of the intein's genomic sequence. Mini-inteins are composed of the self-splicing domains only.
Allowable Qualifiers: DE drug effects
ES ethics
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Protein Splicing (1997-2004)
Public MeSH Note: 2005
History Note: 2005
Related: Exteins MeSH
Protein Precursors MeSH
Protein Splicing MeSH
DeCS ID: 38852
Unique ID: D047668
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2005/01/01
Date of Entry: 2004/07/07
Revision Date: 2008/07/08
Inteins - Preferred
Concept UI M0458475
Scope note The internal fragments of precursor proteins (INternal proTEINS) that are autocatalytically removed by PROTEIN SPLICING. The flanking fragments (EXTEINS) are ligated forming mature proteins. The nucleic acid sequences coding for inteins are considered to be MOBILE GENETIC ELEMENTS. Inteins are composed of self-splicing domains and an endonuclease domain which plays a role in the spread of the intein's genomic sequence. Mini-inteins are composed of the self-splicing domains only.
Preferred term Inteins
Entry term(s) Intein
Intervening Protein Sequence
Intervening Protein Sequences
Intron, Protein
Introns, Protein
Protein Intron
Protein Introns
Protein Sequence, Intervening
Protein Sequences, Intervening
Sequence, Intervening Protein
Sequences, Intervening Protein



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